TAG-72

Tumor-associated glycoprotein 72 (TAG-72), also known as CA72-4, is a glycoprotein found on the surface of many cancer cells, including ovary, breast, colon, lung, and pancreatic cancers. It is a mucin-like molecule with a molar mass of over 1000 kDa. TAG-72 is a tumor marker and can be measured with radioimmunoassays like CA 72-4, which uses the monoclonal antibodies indium (111In) satumomab pendetide and iodine (125I) minretumomab. This assay has a good specificity for gastric cancer, with a correlation to the neoplasia's extension. It is used to identify relapses of the disease and to follow up the treatment. TAG-72 is also the target of the anti-cancer drugs anatumomab mafenatox and minretumomab.

Associated Disease
  • Colon cancer
  • Colorectal cancer

CAR Vector Products Product list:

Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-T-1-M325-2 T cell First CC49 8kb Lentiviral scFv-CD28 Humanized Inquiry
CAR-T-1-M325-G T cell First CC49 8kb Lentiviral scFv-FcεRIγ Humanized Inquiry
CAR-T-1-M325-Z T cell First CC49 8kb Lentiviral scFv-CD3ζ Humanized Inquiry
CAR-T-1-M551-2 T cell First CC49 8kb Lentiviral VHH-CD28 Humanized Inquiry
CAR-T-1-M551-G T cell First CC49 8kb Lentiviral VHH-FcεRIγ Humanized Inquiry
CAR-T-1-M551-Z T cell First CC49 8kb Lentiviral VHH-CD3ζ Humanized Inquiry
CAR-T-2-M325-2G T cell Second CC49 8kb Lentiviral scFv-CD28-FcεRIγ Humanized Inquiry
CAR-T-2-M325-2Z T cell Second CC49 8kb Lentiviral scFv-CD28-CD3ζ Humanized Inquiry
CAR-T-2-M325-4G T cell Second CC49 8kb Lentiviral scFv-CD4-FcεRIγ Humanized Inquiry
CAR-T-2-M325-4Z T cell Second CC49 8kb Lentiviral scFv-CD4-CD3ζ Humanized Inquiry
CAR-T-2-M325-8Z T cell Second CC49 8kb Lentiviral scFv-CD8-CD3ζ Humanized Inquiry
CAR-T-2-M325-BZ T cell Second CC49 8kb Lentiviral scFv-41BB-CD3ζ Humanized Inquiry
CAR-T-2-M325-CZ T cell Second CC49 8kb Lentiviral scFv-b2c-CD3ζ Humanized Inquiry
CAR-T-2-M551-2G T cell Second CC49 8kb Lentiviral VHH-CD28-FcεRIγ Humanized Inquiry
CAR-T-2-M551-2Z T cell Second CC49 8kb Lentiviral VHH-CD28-CD3ζ Humanized Inquiry
CAR-T-2-M551-4G T cell Second CC49 8kb Lentiviral VHH-CD4-FcεRIγ Humanized Inquiry
CAR-T-2-M551-4Z T cell Second CC49 8kb Lentiviral VHH-CD4-CD3ζ Humanized Inquiry
CAR-T-2-M551-8Z T cell Second CC49 8kb Lentiviral VHH-CD8-CD3ζ Humanized Inquiry
CAR-T-2-M551-BZ T cell Second CC49 8kb Lentiviral VHH-41BB-CD3ζ Humanized Inquiry
CAR-T-2-M551-CZ T cell Second CC49 8kb Lentiviral VHH-b2c-CD3ζ Humanized Inquiry
CAR-T-3-M325-2BZ T cell Third CC49 8kb Lentiviral scFv-CD28-41BB-CD3ζ Humanized Inquiry
CAR-T-3-M325-2XZ T cell Third CC49 8kb Lentiviral scFv-CD28-OX40-CD3ζ Humanized Inquiry
CAR-T-3-M551-2BZ T cell Third CC49 8kb Lentiviral VHH-CD28-41BB-CD3ζ Humanized Inquiry
CAR-T-3-M551-2XZ T cell Third CC49 8kb Lentiviral VHH-CD28-OX40-CD3ζ Humanized Inquiry

CAR Viral Particles Product list:

Catalog Antibody
Clone
Packaging
System
Generation Gene
Construct
Promotor Packaging
Cell
Titer Data
sheet
Price
VP-CAR-LC461 CC49 Lentivirus First scFv (CC49)-CD28 CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC462 CC49 Lentivirus First scFv (CC49)-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC463 CC49 Lentivirus First scFv (CC49)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC464 CC49 Lentivirus Second scFv (CC49)-CD28-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC465 CC49 Lentivirus Second scFv (CC49)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC466 CC49 Lentivirus Second scFv (CC49)-CD4-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC467 CC49 Lentivirus Second scFv (CC49)-CD4-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC468 CC49 Lentivirus Second scFv (CC49)-CD8-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC469 CC49 Lentivirus Second scFv (CC49)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC470 CC49 Lentivirus Second scFv (CC49)-b2c-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC471 CC49 Lentivirus Third scFv (CC49)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC472 CC49 Lentivirus Third scFv (CC49)-CD28-OX40-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
CONTACT US

USA
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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
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Tel: 44-207-097-1828

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