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TAG-72

Tumor-associated glycoprotein 72 (TAG-72), also known as CA72-4, is a glycoprotein found on the surface of many cancer cells, including ovary, breast, colon, lung, and pancreatic cancers. It is a mucin-like molecule with a molar mass of over 1000 kDa. TAG-72 is a tumor marker and can be measured with radioimmunoassays like CA 72-4, which uses the monoclonal antibodies indium (111In) satumomab pendetide and iodine (125I) minretumomab. This assay has a good specificity for gastric cancer, with a correlation to the neoplasia's extension. It is used to identify relapses of the disease and to follow up the treatment. TAG-72 is also the target of the anti-cancer drugs anatumomab mafenatox and minretumomab.

Associated Disease
  • Colon cancer
  • Colorectal cancer
  • CAR Vector Products
  • CAR Viral Particles
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CAT Product Name Target SpeciesAntibody CloneAntibody HostReceptor ConstructionVector TypeTargeting Cell Type Inquiry & Datasheet
CAR-T-1-M325-2 Anti-TAG-72 scFv h(CD28) CART, pCDCAR1 Human CC49 Humanized scFv-CD28 Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-M325-G Anti-TAG-72 scFv h(FcεRIγ) CART, pCDCAR1 Human CC49 Humanized scFv-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-M325-Z Anti-TAG-72 scFv h(CD3ζ) CART, pCDCAR1 Human CC49 Humanized scFv-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M325-2G Anti-TAG-72 scFv h(CD28-FcεRIγ) CART, pCDCAR1 Human CC49 Humanized scFv-CD28-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M325-2Z Anti-TAG-72 scFv h(CD28-CD3ζ) CART, pCDCAR1 Human CC49 Humanized scFv-CD28-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M325-4G Anti-TAG-72 scFv h(CD4-FcεRIγ) CART, pCDCAR1 Human CC49 Humanized scFv-CD4-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M325-4Z Anti-TAG-72 scFv h(CD4-CD3ζ) CART, pCDCAR1 Human CC49 Humanized scFv-CD4-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M325-8Z Anti-TAG-72 scFv h(CD8-CD3ζ) CART, pCDCAR1 Human CC49 Humanized scFv-CD8-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M325-BZ Anti-TAG-72 scFv h(41BB-CD3ζ) CART, pCDCAR1 Human CC49 Humanized scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M325-CZ Anti-TAG-72 scFv h(b2c-CD3ζ) CART, pCDCAR1 Human CC49 Humanized scFv-b2c-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-3-M325-2BZ Anti-TAG-72 scFv h(CD28-41BB-CD3ζ) CART, pCDCAR1 Human CC49 Humanized scFv-CD28-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M551-BZ Anti-TAG-72 (CC49) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CC49 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-T-2-M551-CZ Anti-TAG-72 VHH h(b2c-CD3ζ) CAR, [T] Human CC49 Humanized VHH-b2c-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-3-M325-2XZ Anti-TAG-72 scFv h(CD28-OX40-CD3ζ) CART, pCDCAR1 Human CC49 Humanized scFv-CD28-OX40-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-M551-2 Anti-TAG-72 VHH h(CD28) CAR, [T] Human CC49 Humanized VHH-CD28 Lentiviral T cell   Add to Cart   Datasheet
CAR-T-3-M551-2BZ Anti-TAG-72 VHH h(CD28-41BB-CD3ζ) CAR, [T] Human CC49 Humanized VHH-CD28-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M551-2Z Anti-TAG-72 VHH h(CD28-CD3ζ) CAR, [T] Human CC49 Humanized VHH-CD28-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M551-2G Anti-TAG-72 VHH h(CD28-FcεRIγ) CAR, [T] Human CC49 Humanized VHH-CD28-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-3-M551-2XZ Anti-TAG-72 VHH h(CD28-OX40-CD3ζ) CAR, [T] Human CC49 Humanized VHH-CD28-OX40-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-M551-Z Anti-TAG-72 VHH h(CD3ζ) CAR, [T] Human CC49 Humanized VHH-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M551-4Z Anti-TAG-72 VHH h(CD4-CD3ζ) CAR, [T] Human CC49 Humanized VHH-CD4-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M551-4G Anti-TAG-72 VHH h(CD4-FcεRIγ) CAR, [T] Human CC49 Humanized VHH-CD4-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M551-8Z Anti-TAG-72 VHH h(CD8-CD3ζ) CAR, [T] Human CC49 Humanized VHH-CD8-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-M551-G Anti-TAG-72 VHH h(FcεRIγ) CAR, [T] Human CC49 Humanized VHH-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-ZP5895 Anti-TAG-72 (Anatumomab) h(CD28-CD3ζ) CAR, pCDCAR1 Human Anatumomab Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP5896 Anti-TAG-72 (Anatumomab) h(41BB-CD3ζ) CAR, pCDCAR1 Human Anatumomab Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP5897 Anti-TAG-72 (SPM148) h(CD28-CD3ζ) CAR, pCDCAR1 Human SPM148 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP5898 Anti-TAG-72 (SPM148) h(41BB-CD3ζ) CAR, pCDCAR1 Human SPM148 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP5899 Anti-TAG-72 (B72.3) h(CD28-CD3ζ) CAR, pCDCAR1 Human B72.3 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP5900 Anti-TAG-72 (B72.3) h(41BB-CD3ζ) CAR, pCDCAR1 Human B72.3 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP5901 Anti-TAG-72 (SPM536) h(CD28-CD3ζ) CAR, pCDCAR1 Human SPM536 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP5902 Anti-TAG-72 (SPM536) h(41BB-CD3ζ) CAR, pCDCAR1 Human SPM536 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP5903 Anti-TAG-72 (CA72/733) h(CD28-CD3ζ) CAR, pCDCAR1 Human CA72/733 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP5904 Anti-TAG-72 (CA72/733) h(41BB-CD3ζ) CAR, pCDCAR1 Human CA72/733 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP5905 Anti-TAG-72 (CA72/145) h(CD28-CD3ζ) CAR, pCDCAR1 Human CA72/145 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP5906 Anti-TAG-72 (CA72/145) h(41BB-CD3ζ) CAR, pCDCAR1 Human CA72/145 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP5907 Anti-TAG-72 (Satumomab) h(CD28-CD3ζ) CAR, pCDCAR1 Human Satumomab Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP5908 Anti-TAG-72 (Satumomab) h(41BB-CD3ζ) CAR, pCDCAR1 Human Satumomab Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP5909 Anti-TAG-72 (Minretumomab) h(CD28-CD3ζ) CAR, pCDCAR1 Human Minretumomab Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP5910 Anti-TAG-72 (Minretumomab) h(41BB-CD3ζ) CAR, pCDCAR1 Human Minretumomab Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet

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