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MSLN

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This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-ZP8482 A uniCAR [Anti-biotin-dimeric avidin CAR], with a scFv-based CAR Adaptor [Anti-MSLN], a Switchable CAR System Ovarian cancer Lentiviral vector   Add to Cart   Datasheet
CAR-ZP8501 A uniCAR [Anti-leucine zipper CAR], with a mAb-based CAR Adaptor [Anti-MSLN], a Switchable CAR System Ovarian cancer Lentiviral vector   Add to Cart   Datasheet
XS-0722-YF48 TS-Fluc Anti-Human MSLN scFv (SS1) CD28-CD3ζ CAR, pCDCAR1 Human SS1 Mouse 7H-YB-Fluc-EF1a-scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF49 TS-Fluc Anti-Human MSLN scFv (m912) CD28-CD3ζ CAR, pCDCAR1 Human m912 Human 7H-YB-Fluc-EF1a-scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF50 TS-Fluc Anti-Human MSLN scFv (CBL-YF049) CD28-CD3ζ CAR, pCDCAR1 Human CBL-YF049 Humanized 7H-YB-Fluc-EF1a-scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF51 TS-Fluc Anti-Human MSLN scFv (M5) CD28-CD3ζ CAR, pCDCAR1 Human M5 Human 7H-YB-Fluc-EF1a-scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF108 TS-Fluc Anti-Human MSLN scFv (SS1) 4-1BB-CD3ζ CAR, pCDCAR1 Human SS1 Mouse 7H-YB-Fluc-EF1a-scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF109 TS-Fluc Anti-Human MSLN scFv (m912) 4-1BB-CD3ζ CAR, pCDCAR1 Human m912 Human 7H-YB-Fluc-EF1a-scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF110 TS-Fluc Anti-Human MSLN scFv (CBL-YF049) 4-1BB-CD3ζ CAR, pCDCAR1 Human CBL-YF049 Humanized 7H-YB-Fluc-EF1a-scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF111 TS-Fluc Anti-Human MSLN scFv (M5) 4-1BB-CD3ζ CAR, pCDCAR1 Human M5 Human 7H-YB-Fluc-EF1a-scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF168 TS-Fluc Anti-Human MSLN scFv (SS1) CD28-4-1BB-CD3ζ CAR, pCDCAR1 Human SS1 Mouse 7H-YB-Fluc-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF169 TS-Fluc Anti-Human MSLN scFv (m912) CD28-4-1BB-CD3ζ CAR, pCDCAR1 Human m912 Human 7H-YB-Fluc-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF170 TS-Fluc Anti-Human MSLN scFv (CBL-YF049) CD28-4-1BB-CD3ζ CAR, pCDCAR1 Human CBL-YF049 Humanized 7H-YB-Fluc-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF171 TS-Fluc Anti-Human MSLN scFv (M5) CD28-4-1BB-CD3ζ CAR, pCDCAR1 Human M5 Human 7H-YB-Fluc-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF288 TS-IL15 SA Anti-Human MSLN scFv (SS1) 4-1BB-CD3ζ CAR, pCDCAR1 Human SS1 Mouse 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF289 TS-IL15 SA Anti-Human MSLN scFv (m912) 4-1BB-CD3ζ CAR, pCDCAR1 Human m912 Human 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF290 TS-IL15 SA Anti-Human MSLN scFv (CBL-YF049) 4-1BB-CD3ζ CAR, pCDCAR1 Human CBL-YF049 Humanized 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF291 TS-IL15 SA Anti-Human MSLN scFv (M5) 4-1BB-CD3ζ CAR, pCDCAR1 Human M5 Human 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF348 TS-IL15 SA Anti-Human MSLN scFv (SS1) CD28-4-1BB-CD3ζ CAR, pCDCAR1 Human SS1 Mouse 7H-YB-IL15 SA-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF349 TS-IL15 SA Anti-Human MSLN scFv (m912) CD28-4-1BB-CD3ζ CAR, pCDCAR1 Human m912 Human 7H-YB-IL15 SA-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF350 TS-IL15 SA Anti-Human MSLN scFv (CBL-YF049) CD28-4-1BB-CD3ζ CAR, pCDCAR1 Human CBL-YF049 Humanized 7H-YB-IL15 SA-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF351 TS-IL15 SA Anti-Human MSLN scFv (M5) CD28-4-1BB-CD3ζ CAR, pCDCAR1 Human M5 Human 7H-YB-IL15 SA-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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