MUC16

Mucin-16(MUC16) is also known as cancer/carcinoma antigen 125 (CA125) or FLJ14303, which is mainly expressed in ovarian carcinoma. This protein is encoded by MUC16, providing a protective lubricating barrier against particles and infectious agents at mucosal surfaces. It is a membrane associated mucin that possesses a single transmembrane domain, which is a highly characteristic marker of ovarian carcinomas. Although MUC16 is best known as a marker for ovarian cancer, it also be elevated in other cancers, including endometrial cancer, fallopian tube cancer, lung cancer, breast cancer and gastrointestinal cancer.

Associated Disease

CAR Vector Products Product list:

Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-MZ120 T cell Second 4H11 ~8kb Lentiviral scFv-CD137-CD3ζ Mouse Inquiry
CAR-MZ191 T cell First 4H11 ~8kb Lentiviral scFv-CD3ζ Mouse Inquiry
CAR-MZ192 T cell Second 4H11 ~8kb Lentiviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-MZ193 T cell Second 4H11 ~8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-MZ194 T cell Third 4H11 ~8kb Lentiviral scFv-CD28-41BB-CD3ζ Mouse Inquiry

CAR Viral Particles Product list:

Catalog Antibody
Clone
Packaging
System
Generation Gene
Construct
Promotor Packaging
Cell
Titer Data
sheet
Price
VP-CAR-LC818 4H11 Lentivirus Second scFv (4H11)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC819 4H11 Lentivirus Second scFv (4H11)-CD137-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC820 4H11 Lentivirus Second scFv (4H11)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC881 4H11 Lentivirus First scFv (4H11)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC884 4H11 Lentivirus Third scFv (4H11)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
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