Lipid Microparticles

Experienced in the field of novel drug delivery system research for over a decade of years, Creative Biolabs provides a range of customized lipid-based drug delivery formulations and the world’s leading services to help customers’ projects get improvement.

What are Lipid Microparticles?

Lipid microparticles are micro-scale drug delivery systems, of which the particle size ranges larger than 1 μm. Similar to other lipid particulate systems particular lipid nanoparticles, lipid microparticles consist of a drug containing core and lipids shell. The difference between nanoparticles and microparticles is size or diameter of the particles, which affects many properties of the carriers such as aggregation, permeability across the biological membranes, cell entry and tissue retention as well as drug loading efficiency. Lipid microparticles are possible to be particulate dispersions or solid particles with microcapsules and microspheres two common micromorphologies.

Fig.1 Microparticles and nanoparticles for drug delivery.

Drug Delivery Mechanism of Lipid Microparticles

As a promising drug carrier system, lipid microparticles are extensively applied for delivery pharmaceutical ingredients with poor solubility and bioavailability. Lipid microparticles delivery system can realize drug release in a sustained way by encapsulation limiting the biological fluid access into the drug until the time of degradation. The inner core delivered drugs also are able to be released in a controlled manner and targeted manner at a predetermined rate, systemically or locally for a specified period of time. Delivery or release mechanisms generally are three different ways including diffusion, polymer degradation, and hydrolysis or erosion.

Features of Lipid Microparticles

Lipid microparticles drug carriers can protect the inner delivered pharmaceutical drug from adverse affection by environment via encapsulation. This type of drug delivery system plays a critical role in improving the bioavailability of conventional drugs and minimizing side effects. Compared to conventional formulations, lipid microparticles offer numerous biomedical superiorities, such as:

• Masking unpleasant taste of drugs and improving compliance of patients
• The decrease of incompatibilities and non-site release of inner drugs
• Stabilization of sensitive drug substances and solubility of poorly soluble molecules
• Particle in micro-scale increases permeability and bioavailability of the entrapped compounds
• Prolonged release of loaded drug and drug release in controlled, sustained, and targeted manners

Despite these advantages, lipid microparticles still have imperfections and some aspects to be improved such as sensitive to changes as temperature, pH and higher costs.

Our Advantages about Lipid Microparticles system

• Advanced particles platforms for new drug delivery system productions and services
• Scientific teams specialized in pharmaceutical drugs delivery
• Customized different lipid microparticles formulations and services
• Years of industry experience on lipid drug delivery especially lipid microparticles

For your lipid microparticles carries researches or programs, Creative Biolabs possesses absolute advantages to fulfill customers’ specific demands with perfect solutions and strategies. Our work and high-quality services comprise of various lipid drug carriers formulations and other related services.

Please feel free to contact us and communicate with us for more information. Our service team is available all the times.

For Research Use Only. Not For Clinical Use