Carboxylic Acid-Doxorubicin Liposome (PEGylated) (CAT#: CLBD010LY)

Description
This formulation is Doxorubicin Liposome (PEGylated) with the carboxyl group, which can be activated by EDC (1-ethyl-3-[3-dimethylaminopropyl] carbodiimide) and react with sulfo-NHS (N-hydroxysulfosuccinimide) to produce a significantly more stable and more soluble active intermediate (NHS ester). The intermediate can covalently conjugate to the amine group on the proteins, peptides or antibodies through displacement of sulfo-NHS group by amine.
Lipid Composition
HSPC, Cholesterol, DSPE-PEG(2000), DSPE-PEG(2000)-Carboxylic Acid
Encapsulated Drug
Doxorubicin
Buffer
PBS, pH 6.0
Storage
Store in dark at +4°C and do not freeze
Size
100 nm
Quantity
5mL (available in lyophilized powder)
Dosage
Molecular Structure
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