Egg PC:Chol (70:30) Liposomes (CAT#: LDLY-0123-LY83)

The combination of PC and cholesterol enhances the stability and permeability of these liposomes, making them effective carriers for both hydrophilic and hydrophobic drugs. The cholesterol component helps in modulating the fluidity of the liposome bilayer, crucial for controlled release mechanisms.

These liposomes are commonly prepared using the thin-film hydration technique followed by extrusion or sonication to achieve uniform size distribution. This method ensures the encapsulation efficiency and reproducibility required for research and clinical applications.

Yes, these liposomes can be modified with targeting ligands or antibodies to facilitate targeted delivery. This allows the liposomes to selectively bind to specific cells or tissues, enhancing the therapeutic efficacy and reducing side effects.

While the inclusion of cholesterol generally enhances stability, these liposomes must be stored properly to maintain their structural integrity. They should be stored at 2-8°C and protected from light to prevent oxidation and degradation of lipids.

Beyond drug delivery, these liposomes are used in the study of lipid bilayer behavior, membrane-protein interactions, and as model systems for understanding cellular membrane dynamics. Their biocompatibility makes them ideal for physiological studies.