Phospholipids

Phospholipids are main components of the cellular membrane with characteristics of excellent biocompatibility and especial amphiphilicity. When introduced into aqueous milieu, the amphiphilic phospholipids self-assembly generates different structures depending on their properties, for example, bilayers, micelles, and liposomes. The molecule structure of phospholipid consists of a hydrophilic head group and hydrophobic acyl chains linked to the alcohol. The variation in head groups, acyl chains, and alcohols lead to a variety of phospholipids with different shape and charge, which provides various options for phospholipid-based drug delivery.

Table 1. Head group of common phospholipids

Creative Biolabs offers various phospholipids reagents to customers all over the world. As one of the leading companies in lipid-based drug delivery, our high-quality phospholipid products are synthesized and purified using the advanced technology platform and have been provided worldwide for years with good feedback. All of our products meet stringent quality and stability control standards, which provides reliability to accelerate your projects and provide solutions for therapeutic drugs delivery and development of next-generation mRNA vaccines. Our phospholipids products include:

• Phosphatidic Acid & Lysophosphatidic Acid
• Phosphatidylcholine & Lysophosphatidylcholine
• Phosphatidylethanolamine & Lysophosphatidylethanolamine
• Phosphatidylglycerol & Lysophosphatidylglycerol
• Phosphoinositide & Lysophosphatidylinositol
• Phosphatidylserine & Lysophosphatidylserine
• Cardiolipin
• Ether Lipids

Figure 1. Molecular structure of phospholipids

Phospholipids have been widely used in the preparation of liposomes, ethosomes, and other nanoformulations for oral or parenteral drugs delivery. Such nanostructures could improve bioavailability and reduce the toxicity of traditional drugs, and protect therapeutic substances (antibodies, mRNA, etc.) from being degraded. Besides, the phospholipids modified with different molecules can form multifunctional liposomes.

As a professional contract manufacturer in the field of lipid-based drug delivery, we are providing high-quality phospholipid products for our customers. In addition, Creative Biolabs also offers custom phospholipid services to design and synthesize ideal products according to your requirements. Our state-of-the-art equipment and experienced research teams can guarantee the quality and effectiveness of our products.

Please feel free to contact us for more information about our products & services. We will get back to you as soon as possible.

For Research Use Only. Not For Clinical Use