DSPC Liposomes (CAT#: LDLY-0123-LY13)

Description
Liposomes are extensively used to study the interaction of proteins, peptides and other molecules with the surface of a lipid membrane. This product is mainly made of saturated Phosphatidylcholine (PC). PC is the most abundant phospholipid in eukaryotic cell membranes and it can form lipid bilayers. PC also plays a important role in liposome.
Lipid Composition
DSPC
Applications
Control liposomes, Membrane biology
Format
Liquid
Concentration
10mg/mL
Hydration Solution
PBS, pH 7.4
External Solution
PBS, pH 7.4
Storage
2°C - 8°C (do not freeze)
Size
70-120 nm
Shelf Life
6 months
Quantity
5mL (available in lyophilized powder)
Download
DataSheet MSDS
FAQs Published Data Customer Reviews Related Sections
  1. How are DSPC Liposomes formulated?

    They are made from 100% DSPC, forming lipid bilayers under sterile conditions.

  2. What precaution should be taken regarding the storage of DSPC Liposomes?

    Store them in a refrigerator at 4°C to prevent hydrolysis and avoid freezing to maintain their integrity.

  3. What are the advantages of using saturated phosphatidylcholine like DSPC in liposomes?

    Saturated PC, such as DSPC, provides stability and uniformity in lipid bilayers.

  4. Are DSPC Liposomes suitable for in vivo studies?

    As they are for research purposes, they can be used in laboratory animal studies under the specified protocols.

  5. How should multiple aliquots be taken from DSPC Liposome vials?

    Take extreme care to avoid contamination and handle the vial under a sterile hood.

DSPC Liposomes-fig1


The energy of van der waals interactions, electrostatic interactions and overall energy for DPSM and DSPC liposomes.

This study used coarse-grained molecular simulations to investigate the effect of phospholipid types on liposome formation and stability. In order to obtain the final stable state of liposomal structures, researchers conducted various energy analyses (van der waals, electrostatic energies and overall energy). Figures A, B, and C illustrate the van der waals energies, electrostatic energies, and overall energy for DPSM and DSPC liposomes, respectively. The results indicate that the energy values for DPSM liposomes are greater than DSPC liposome, suggesting that DPSM liposomes demonstrate superior stability. In this study, DSPC liposomes serve as a model system, allowing researchers to investigate how specific lipid characteristics affect the stability and formation of liposomes. The insights gained from the DSPC model are essential for understanding the broader implications of liposome design and functionality in pharmaceutical applications.

Hashemzadeh, H., H. Javadi, and M. H. Darvishi. "Study of Structural stability and formation mechanisms in DSPC and DPSM liposomes: A coarse-grained molecular dynamics simulation." Scientific reports 10.1 (2020): 1837.

Distributed under Open Access license CC BY 4.0, without modification.

  • Superior Membrane Models
    These liposomes have provided us with superior synthetic membrane models, facilitating our lipid research.
  • Unmatched Consistency
    The consistent behavior of DSPC Liposomes across experiments has been invaluable to our studies.
  • Excellent for Lipid Research
    Perfect for detailed investigations into lipid bilayers and membrane properties.
  • Enhanced Research Quality
    Greatly enhanced the quality and reproducibility of our lipid interaction research.

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For Research Use Only. Not For Clinical Use

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