Mannosylated Clodronate Liposome (CAT#: CLBD001LYm)

Description
Mannosylated Clodronate Liposome is a multilamellar liposome suspension in which clodronate is encapsulated in the aqueous compartments of the mannosylated liposomes. When animals or cells are treated with Mannosylation Clodronate Liposome, phagocytic cells recognize the liposomes as invading foreign particles and proceed to remove the liposomes from the local tissue or serum via phagocytosis. The liposomes then release clodronate into the cytosol resulting in cell death. Non-encapsulated clodronate cannot cross the cell membrane to initiate cell death.
Encapsulated Drug
Clodronate, Disodium Salt
Concentration
10mg/mL
Mannosylation
4-Aminophenyl-alpha-D-mannopyranoside
Buffer
PBS, pH 7.4
Storage
Store in dark at +4°C and do not freeze
Size
1.5-2 µm
Quantity
5mL (available in lyophilized powder)
Dosage
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DataSheet MSDS
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