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Custom ssRNA Synthesis


Creative Biolabs is an industry leader in manufacturing high-quality RNA oligos for research, diagnostics, and therapeutics. We are specialized in synthesizing highly modified RNA oligos and providing high-quality and cost-effective custom single-stranded Ribonucleic Acid (ssRNA) oligos with flexible synthesis scales to meet the diverse needs of customers.

Application of ssRNA

Custom ssRNA Synthesis

Today, synthetic oligos are important tools for scientists and have many applications in molecular biology and genetic diagnostics. They are expected to become important tools for molecular medicine and the development of novel therapeutic strategies. Among them, ssRNA is widely used for basic research and in vitro diagnostics, such as reference RNA for developing in vitro diagnostic assays, internal control RNA for performance control (such as RNA isolation, reverse transcription and qPCR amplification/detection), and positive control RNA for controlling high detection quality, etc.

Custom ssRNA Synthesis

Creative Biolabs offers custom synthesis services for ssRNA oligos with a variety of modifications, scales, and purity. All the ssRNA oligos are synthesized using our proprietary nucleic acid technology and purified using RNase free PAGE electrophoresis combined with HPLC. To ensure the highest quality of ssRNA oligos, all RNA oligos are identified by mass spectrometry. Therefore, all ssRNA oligos manufactured at Creative Biolabs undergo quality control analysis by PAGE, HPLC, and/or MS.

Custom ssRNA Synthesis Specifications
Scales
  • Small-scale: 0.05, 0.2, 0.4 & 1.0-10 µmol
  • Large-scale synthesis
Purification
  • Desalt, Cartridge, HPLC or PAGE
  • Recommend purification for sequences >30 bases
Sequence Length
  • Any length, from dozens of bases to more than a hundred bases
Modifications
  • 5' Modification: 5' Fluorescein, 5' Phosphorylation, 5' Biotin, etc.
  • 3' Modification: 3' Fluorescein, 3' Phosphorylation, 3' Biotin, etc.
  • Internal modification: Phosphorothioate, 2'-Ome, 2'-F(N), Inosine, etc.
  • Other external modifications
Quality Control
  • 100% mass spectrometry
Format
  • Supplied dry in tubes
  • Pooling & aliquoting available (inquire for feasibility)

Features and Benefits

Delivery Specifications:

Turnaround time Deliverables
  • 5-10 business days
  • Your desired oligonucleotides in tubes
  • Certificate of analysis (COA)
  • MS report
  • HPLC report
  • CGE report

Creative Biolabs will support your RNA research with our expertise in high-quality modified ssRNA oligos synthesis and excellent technical support. Whether you need standard ssRNA oligos or highly modified nucleic acid sequences, we can synthesize with your required scale and purity level. If you have a need, please contact us and we will be happy to discuss your project needs.

For Lab Research Use Only, Not for Human or Animal Therapeutic Use.

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For Lab Research Use Only, Not for Human or Animal Therapeutic Use.

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