Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy.
What are the main features of 0.5% DiI Encapsulated DOTAP liposomes?
These liposomes are cationic and used for delivering genetic materials like DNA and RNA. The DiI component, a fluorescent dye, helps in tracking and visualizing the liposomes.
How does the inclusion of DiI benefit the use of these liposomes in research?
The fluorescent property of DiI allows for the easy tracking and visualization of the liposomes during experiments, aiding in understanding their behavior and interaction with cells.
Are there any specific considerations for storing and handling this liposome formulation?
As with many liposomal products, they should be stored at controlled temperatures, typically 2-8°C, and protected from light to maintain stability and fluorescence intensity.
Can 0.5% DiI Encapsulated DOTAP liposomes be used with other experimental agents?
Yes, but compatibility with other agents should be evaluated. Interactions with additional substances should be checked to ensure they do not destabilize the liposomes or affect the encapsulated dye.
Enhanced Visualization for Research
Creative Biolabs' 0.5% DiI Encapsulated DOTAP Liposomes provide excellent visualization in cellular experiments. Their fluorescent properties greatly aid in tracking and analysis.
Superior Transfection Efficiency
Utilizing Creative Biolabs' liposomes has resulted in notably high transfection efficiency in our gene delivery studies. Their formulation balances charge ratios effectively for optimal DNA/RNA delivery.
Reliable and Consistent Quality
I appreciate the consistency and reliability of Creative Biolabs' product. The liposomes maintain their integrity, providing reproducible results in our experiments.
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For Research Use Only. Not For Clinical Use