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CAR Targeting Carcinoma-specific Antigens

As a leading and reliable service provider, Creative Biolabs is well known worldwide for its breakthrough in CAR production system. Based on targeting carcinoma-specific antigens in the follow table, our outstanding scientists have constructed diverse CAR-T cells or CAR NK cells targeting these antigens. In addition to these, Creative Biolabs can also customize CAR product according to your special requirements.

CAR Targeting Carcinoma-specific Antigens Vicki Brower. The CAR T-Cell Race. The scientist. 2015

As a group of cancer, carcinoma usually starts from skin and spreads to other organs of the body. It accounts for 90% of all cancers, which mostly occurs in adults, with the DNA mutation as its main cause. Based on the tissue which cancer cells arise from, the primary carcinoma category includes breast cancer, prostate cancer, colorectal cancer, lung malignancy, adenocarcinomas, cervical carcinoma, melanoma and renal cell carcinoma. The most common symptom is lump under the skin, while there’re some other symptoms such as skin discolorations, pains. Although few strategies show effectiveness in carcinoma treatment, immunotherapy has performed great potential as a promising approach to treat carcinoma, such as CAR modified T cells or natural killer (NK) cells. Experts from Creative Biolabs can offer various CAR-T cell or NK cells construction services according to your request.

Based on a great amount of experiments, we are confident our first-class CAR products can greatly accelerate your project process. Please feel free to contact us at any time.

Products against Carcinoma-specific antigens

Associated malignancy Target antigen Receptor type Product
Renal cell carcinoma (RCC) Carbonic anhydrase IX (CAIX) scFv-CD28-41BB-CD3ζ CAR-MZ204
CSPG4 scFv-CD28-CD3ζ CAR-LC134
G250 epitope iRGD-scFv-CD28-41BB-CD3ζ CAR-LC371
VEGFR-2 scFv-CD28-41BB-CD3ζ CAR-LC132
scFv-CD28-CD3ζ CAR-LC133
Melanoma EGFR scFv-CD3ζ CAR-LC097
scFv-CD28-CD3ζ CAR-LC098
scFv-CD28-41BB-CD3ζ CAR-LC100
Trop2 scFv-CD28-41BB-CD3ζ CAR-LC190
PD-L1 PD1-41BB-CD3ζ CAR-LC282
Cs-1 scFv (SLAMF7)-CD28-41BB-CD3ζ/scFv (FN)-cMYCmu CAR-LC365
BCMA scFv-CD28-41BB-CD3ζ CAR-T-3-L335-2BZ
CS1 scFv-CD28-OX40-CD3ζ CAR-NK-3-M329-2XZ
CSH1 scFv-CD28-41BB-CD3ζ CAR-T-3-L349-2BZ
HMW-MAA scFv-CD28-41BB-CD3ζ CAR-T-3-M318-2BZ
NY-ESO-1 scFv-CD28-41BB-CD3ζ CAR-T-3-M323-2BZ
GD3 scFv-CD28-41BB-CD3ζ CAR-T-3-M317-2BZ
MART-1(DMF5) scFv-CD28-41BB-CD3ζ CAR-T-3-M310-2BZ
CD56 scFv-CD28-41BB-CD3ζ CAR-T-3-M312-2BZ
gp100 VHH-41BB-CD3ζ CAR-T-2-M552-BZ
Lung malignancy Mesothelin scFv-CD28-41BB-CD3ζ CAR-LC054
scFv-CD3ζ CAR-LC023
scFv-CD28-CD3ζ CAR-LC024
ALK scFv-CD28-41BB-CD3ζ CAR-LC103
Fibroblast activation protein (FAP) scFv-41BB-CD3ζ CAR-LC224
CD87 scFv-41BB-CD3ζ-IL12 CAR-LC265
Tissue factor Protein-41BB-CD3ζ CAR-LC288
TF scFv-CD28-OX40-CD3ζ CAR-T-3-L406-2XZ
Colorectal cancer CEA scFv-CD28-41BB-CD3ζ CAR-T-3-M314-2BZ
EGP-2 scFv-CD28-41BB-CD3ζ CAR-T-3-M316-2BZ
TAG-72 scFv-CD28-41BB-CD3ζ CAR-T-3-M325-2BZ
CD276 scFv-CD28-CD3ζ CAR-LC162
EpCAM scFv-CD28-41BB-CD3ζ CAR-LC181
HLA-A2-WT1DB126 scFv-CD28-FcγR1γ CAR-LC266
Prostate cancer PSMA scFv-CD28-OX40-CD3ζ CAR-T-3-L336-2XZ
PSCA scFv-CD28-CD3ζ CAR-MZ157
Breast cancer CD8 scFv-CD28-41BB-CD3ζ CAR-T-3-L348-2BZ
ErbB2 scFv-CD28-41BB-CD3ζ CAR-T-3-L337-2BZ
MUC1  scFv-CD28-41BB-CD3ζ CAR-T-3-M322-2BZ
TEM8 scFv-CD28-41BB-CD3ζ CAR-T-3-L343-2BZ
SSEA4 scFv-41BB-CD3ζ CAR-LC001
CD33 scFv-CD28-CD3ζ CAR-LC155
HER2 scFv-41BB-CD3ζ CAR-LC172
NY-BR-1 scFv-CD28-41BB-CD3ζ CAR-LC220
CD44 scFv-CD28-CD3ζ CAR-LC226
CD47 scFv (CD47)-CD28-41BB-CD3ζ/scFv (TAZ)-TET2 CAR-LC364

All services and products are only for lab research use, not for any clinical diagnosis or treatment.

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