BCMA
B Cell Maturation Antigen (BCMA), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17),is encoded by TNFRSF17 gene in human. It is a transmembrane signaling protein preferentially expressed on plasma cells. It is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). Its ligands including BAFF and A Proliferation Inducing Ligand (APRIL). BCMA is involved in JNK and NF-kB activation pathways that induce B-cell development and autoimmune responses. BCMA has been implicated in autoimmune disorders as well as B-lymphocyte malignancies, leukemia, lymphomas, and multiple myeloma.
Associated Disease
| Catalog | Targeting Cell Type |
Generation | Antibody Clone |
Vector Length |
Vector Type |
Vector Design | Antibody Host |
Data sheet |
Price |
| CAR-LC002 | T cell | Second | J6M0 | ~8kb | Lentiviral | scFv-41BB-CD3ζ | Human |
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Inquiry |
| CAR-LC041 | T cell | Second | C12A3.2 | ~8kb | Lentiviral | scFv-CD28-CD3ζ | Mouse |
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Inquiry |
| CAR-LC042 | T cell | Second | C11D5.3 | ~8kb | Lentiviral | scFv-CD28-CD3ζ | Mouse |
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Inquiry |
| CAR-LC043 | T cell | Second | C11D5.3 | ~8kb | Lentiviral | scFv-41BB-CD3ζ | Mouse |
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Inquiry |
| CAR-LC044 | T cell | Second | C11D5.3 | ~8kb | Lentiviral | scFv-OX40-CD3ζ | Mouse |
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Inquiry |
| CAR-LC045 | T cell | Third | C11D5.3 | ~8kb | Lentiviral | scFv-41BB-OX40-CD3ζ | Mouse |
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Inquiry |
| CAR-LC135 | T cell | Second | P5A2 | ~8kb | Lentiviral | scFv-41BB-CD3ζ | Human |
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Inquiry |
| CAR-LC136 | T cell | Second | A02_Rd4 | ~8kb | Lentiviral | scFv-41BB-CD3ζ | Human |
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Inquiry |
| CAR-LC137 | T cell | Second | P5C1 | ~8kb | Lentiviral | scFv-41BB-CD3ζ | Human |
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Inquiry |
| CAR-LC138 | T cell | Second | C01_Rd4 | ~8kb | Lentiviral | scFv-41BB-CD3ζ | Human |
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Inquiry |
| CAR-LC139 | T cell | Second | COMBO_Rd4 | ~8kb | Lentiviral | scFv-41BB-CD3ζ | Human |
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Inquiry |
| CAR-LC140 | T cell | Second | L3PY/H2DY | ~8kb | Lentiviral | scFv-41BB-CD3ζ | Human |
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Inquiry |
| CAR-LC141 | T cell | Second | P6AP-V1 | ~8kb | Lentiviral | scFv-41BB-CD3ζ | Human |
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Inquiry |
| CAR-LC260 | T cell | Second | C12A3.2 | ~8kb | Lentiviral | scFv-41BB-CD3ζ | Mouse |
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Inquiry |
| CAR-LC261 | T cell | Second | BC50 | ~8kb | Lentiviral | scFv-41BB-CD3ζ | Mouse |
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Inquiry |
| CAR-LC262 | T cell | Second | BC30 | ~8kb | Lentiviral | scFv-41BB-CD3ζ | Mouse |
|
Inquiry |
| CAR-LC285 | T cell | Third | ~8kb | Retroviral | dAPRIL-CD28-OX40-CD3ζ | Human |
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Inquiry | |
| CAR-LC286 | T cell | Third | ~8kb | Retroviral | dAPRIL-CD8STK-CD28-OX40-CD3ζ | Human |
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Inquiry | |
| CAR-MZ014 | T cell | Second | C13F12.1 | ~8kb | Lentiviral | scFv-41BB-CD3ζ | Humanized |
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Inquiry |
| CAR-MZ122 | T cell | Second | 11D5-3 | ~8kb | Retroviral | scFv-CD28-CD3ζ | Mouse |
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Inquiry |
| CAR-T-1-L335-2 | T cell | First | MM0108-3D44 | 8kb | Lentiviral | scFv-CD28 | Mouse |
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Inquiry |
| CAR-T-1-L335-G | T cell | First | MM0108-3D44 | 8kb | Lentiviral | scFv-FcεRIγ | Mouse |
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Inquiry |
| CAR-T-1-L335-Z | T cell | First | MM0108-3D44 | 8kb | Lentiviral | scFv-CD3ζ | Mouse |
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Inquiry |
| CAR-T-2-L335-2G | T cell | Second | MM0108-3D44 | 8kb | Lentiviral | scFv-CD28-FcεRIγ | Mouse |
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Inquiry |
| CAR-T-2-L335-2Z | T cell | Second | MM0108-3D44 | 8kb | Lentiviral | scFv-CD28-CD3ζ | Mouse |
|
Inquiry |
| CAR-T-2-L335-4G | T cell | Second | MM0108-3D44 | 8kb | Lentiviral | scFv-CD4-FcεRIγ | Mouse |
|
Inquiry |
| CAR-T-2-L335-4Z | T cell | Second | MM0108-3D44 | 8kb | Lentiviral | scFv-CD4-CD3ζ | Mouse |
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Inquiry |
| CAR-T-2-L335-8Z | T cell | Second | MM0108-3D44 | 8kb | Lentiviral | scFv-CD8-CD3ζ | Mouse |
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Inquiry |
| CAR-T-2-L335-BZ | T cell | Second | MM0108-3D44 | 8kb | Lentiviral | scFv-41BB-CD3ζ | Mouse |
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Inquiry |
| CAR-T-2-L335-CZ | T cell | Second | MM0108-3D44 | 8kb | Lentiviral | scFv-b2c-CD3ζ | Mouse |
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Inquiry |
| CAR-T-3-L335-2BZ | T cell | Third | MM0108-3D44 | 8kb | Lentiviral | scFv-CD28-41BB-CD3ζ | Mouse |
|
Inquiry |
| CAR-T-3-L335-2XZ | T cell | Third | MM0108-3D44 | 8kb | Lentiviral | scFv-CD28-OX40-CD3ζ | Mouse |
|
Inquiry |
| Catalog | Antibody Clone |
Packaging System |
Generation | Gene Construct |
Promotor | Packaging Cell |
Titer | Data sheet |
Price |
| VP-CAR-LC25 | MM0108-3D44 | Lentivirus | First | scFv (MM0108-3D44)-CD28 | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC26 | MM0108-3D44 | Lentivirus | First | scFv (MM0108-3D44)-FcεRIγ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC27 | MM0108-3D44 | Lentivirus | First | scFv (MM0108-3D44)-CD3ζ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC28 | MM0108-3D44 | Lentivirus | Second | scFv (MM0108-3D44)-CD28-FcεRIγ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC29 | MM0108-3D44 | Lentivirus | Second | scFv (MM0108-3D44)-CD28-CD3ζ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC30 | MM0108-3D44 | Lentivirus | Second | scFv (MM0108-3D44)-CD4-FcεRIγ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC31 | MM0108-3D44 | Lentivirus | Second | scFv (MM0108-3D44)-CD4-CD3ζ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC32 | MM0108-3D44 | Lentivirus | Second | scFv (MM0108-3D44)-CD8-CD3ζ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC33 | MM0108-3D44 | Lentivirus | Second | scFv (MM0108-3D44)-41BB-CD3ζ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC34 | MM0108-3D44 | Lentivirus | Second | scFv (MM0108-3D44)-b2c-CD3ζ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC35 | MM0108-3D44 | Lentivirus | Third | scFv (MM0108-3D44)-CD28-41BB-CD3ζ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC36 | MM0108-3D44 | Lentivirus | Third | scFv (MM0108-3D44)-CD28-OX40-CD3ζ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC510 | Lentivirus | Second | scFv-41BB-CD3ζ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry | |
| VP-CAR-LC533 | C12A3.2 | Lentivirus | Second | scFv (C12A3.2)-CD28-CD3ζ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC534 | C11D5.3 | Lentivirus | Second | scFv (C11D5.3)-CD28-CD3ζ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC535 | C11D5.3 | Lentivirus | Second | scFv (C11D5.3)-41BB-CD3ζ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC536 | C11D5.3 | Lentivirus | Second | scFv (C11D5.3)-OX40-CD3ζ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC537 | C11D5.3 | Lentivirus | Third | scFv (C11D5.3)-41BB-OX40-CD3ζ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC619 | P5A2 | Lentivirus | Second | scFv (P5A2)-41BB-CD3ζ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC620 | A02_Rd4 | Lentivirus | Second | scFv (A02_Rd4)-41BB-CD3ζ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC621 | P5C1 | Lentivirus | Second | scFv (P5C1)-41BB-CD3ζ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC622 | C01_Rd4 | Lentivirus | Second | scFv (C01_Rd4)-41BB-CD3ζ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC623 | COMBO_Rd4 | Lentivirus | Second | scFv (COMBO_Rd4)-41BB-CD3ζ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC624 | L3PY/H2DY | Lentivirus | Second | scFv (L3PY/H2DY)-41BB-CD3ζ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC625 | P6AP-V1 | Lentivirus | Second | scFv (P6AP-V1)-41BB-CD3ζ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC730 | C12A3.2 | Lentivirus | Second | scFv (C12A3.2)-41BB-CD3ζ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC731 | BC50 | Lentivirus | Second | scFv (BC50)-41BB-CD3ζ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC732 | BC30 | Lentivirus | Second | scFv (BC30)-41BB-CD3ζ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC745 | C13F12.1 | Lentivirus | Second | scFv (C13F12.1)-41BB-CD3ζ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
| VP-CAR-LC821 | 11D5-3 | Lentivirus | Second | scFv (11D5-3)-CD28-CD3ζ | CMV | 293T | > 10⁷ IFU/ml |
|
Inquiry |
USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-381-2994
Fax: 1-631-207-8356
Email:
Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-097-1828
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