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BCMA

B Cell Maturation Antigen (BCMA), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17),is encoded by TNFRSF17 gene in human. It is a transmembrane signaling protein preferentially expressed on plasma cells. It is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). Its ligands including BAFF and A Proliferation Inducing Ligand (APRIL). BCMA is involved in JNK and NF-kB activation pathways that induce B-cell development and autoimmune responses. BCMA has been implicated in autoimmune disorders as well as B-lymphocyte malignancies, leukemia, lymphomas, and multiple myeloma.

Associated Disease
  • T cell lymphoma
  • Multiple myeloma
  • Acute myelomonocytic leukemia (AMML)
  • Acute monocytic leukemia
  • Follicular lymphoma
  • CAR Vector Products
  • CAR Viral Particles
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CAT Product Name Target SpeciesAntibody CloneAntibody HostReceptor ConstructionVector TypeTargeting Cell Type Inquiry & Datasheet
CAR-T-1-L335-2 Anti-BCMA scFv h(CD28) CART, pCDCAR1 Human MM0108-3D44 Rat scFv-CD28 Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-L335-G Anti-BCMA scFv h(FcεRIγ) CART, pCDCAR1 Human MM0108-3D44 Rat scFv-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-L335-Z Anti-BCMA scFv h(CD3ζ) CART, pCDCAR1 Human MM0108-3D44 Rat scFv-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-L335-2G Anti-BCMA scFv h(CD28-FcεRIγ) CART, pCDCAR1 Human MM0108-3D44 Rat scFv-CD28-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-L335-2Z Anti-BCMA scFv h(CD28-CD3ζ) CART, pCDCAR1 Human MM0108-3D44 Rat scFv-CD28-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-L335-4G Anti-BCMA scFv h(CD4-FcεRIγ) CART, pCDCAR1 Human MM0108-3D44 Rat scFv-CD4-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-L335-4Z Anti-BCMA scFv h(CD4-CD3ζ) CART, pCDCAR1 Human MM0108-3D44 Rat scFv-CD4-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-L335-8Z Anti-BCMA scFv h(CD8-CD3ζ) CART, pCDCAR1 Human MM0108-3D44 Rat scFv-CD8-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-L335-BZ Anti-BCMA scFv h(41BB-CD3ζ) CART, pCDCAR1 Human MM0108-3D44 Rat scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-L335-CZ Anti-BCMA scFv h(b2c-CD3ζ) CART, pCDCAR1 Human MM0108-3D44 Rat scFv-b2c-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-3-L335-2BZ Anti-BCMA scFv h(CD28-41BB-CD3ζ) CART, pCDCAR1 Human MM0108-3D44 Rat scFv-CD28-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC041 Anti-BCMA (C12A3.2) h(CD28-CD3ζ) CAR, pCDCAR1 Human C12A3.2 Mouse scFv-CD28-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC135 Anti-BCMA (P5A2) h(41BB-CD3ζ) CAR, pCDCAR1 Human P5A2 Human scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC136 Anti-BCMA (A02_Rd4) h(41BB-CD3ζ) CAR, pCDCAR1 Human A02_Rd4 Human scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC002 Anti-BCMA (J6M0)h(41BB-CD3ζ) CAR, pCDCAR1 Human J6M0 Human scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC260 Anti-BCMA (C12A3.2) h(41BB-CD3ζ) CAR, pCDCAR1 Human C12A3.2 Mouse scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-3-L335-2XZ Anti-BCMA scFv h(CD28-OX40-CD3ζ) CART, pCDCAR1 Human MM0108-3D44 Rat scFv-CD28-OX40-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC042 Anti-BCMA (C11D5.3) h(CD28-CD3ζ) CAR, pCDCAR1 Human C11D5.3 Mouse scFv-CD28-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC137 Anti-BCMA (P5C1) h(41BB-CD3ζ) CAR, pCDCAR1 Human P5C1 Human scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC138 Anti-BCMA (C01_Rd4) h(41BB-CD3ζ) CAR, pCDCAR1 Human C01_Rd4 Human scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC139 Anti-BCMA (COMBO_Rd4) h(41BB-CD3ζ) CAR, pCDCAR1 Human COMBO_Rd4 Human scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC140 Anti-BCMA (L3PY/H2DY) h(41BB-CD3ζ) CAR, pCDCAR1 Human L3PY/H2DY Human scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC043 Anti-BCMA (C11D5.3) h(41BB-CD3ζ) CAR, pCDCAR1 Human C11D5.3 Mouse scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC044 Anti-BCMA (C11D5.3) h(OX40-CD3ζ) CAR, pCDCAR1 Human C11D5.3 Mouse scFv-OX40-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC045 Anti-BCMA (C11D5.3) h(41BB-OX40-CD3ζ) CAR, pCDCAR1 Human C11D5.3 Mouse scFv-41BB-OX40-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-MZ014 Anti-BCMA (C13F12.1) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human C13F12.1 Humanized scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-MZ122 Anti-BCMA (11D5-3) h(CD28-CD3ζ) CAR, pCDCAR1 Human 11D5-3 Mouse scFv-CD28-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC261 Anti-BCMA (BC50) h(41BB-CD3ζ) CAR, pCDCAR1 Human BC50 Mouse scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC262 Anti-BCMA (BC30) h(41BB-CD3ζ) CAR, pCDCAR1 Human BC30 Mouse scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC285 Anti-TNFRSF17 h(CD28-OX40-CD3ζ) Ligand-based CAR, pCDCAR1 Human Human dAPRIL-CD28-OX40-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC286 Anti-TNFRSF17 h(CD8STK-CD28-OX40-CD3ζ) Ligand-based CAR, pCDCAR1 Human Human dAPRIL-CD8STK-CD28-OX40-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC141 Anti-BCMA (P6AP-V1) h(41BB-CD3ζ) CAR, pCDCAR1 Human P6AP-V1 Human scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-YF175 Anti-BCMA (CBL-YF057) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBL-YF057 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF115 Anti-BCMA (J22.9) h(CD28-CD3ζ) CAR, pCDCAR1 Human J22.9 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF176 Anti-BCMA (CBL-YF057) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBL-YF057 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF131 Anti-BCMA (7G2) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human 7G2 Humanized scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF132 Anti-BCMA (7G2) h(CD28-CD3ζ) CAR, pCDCAR1 Human 7G2 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF133 Anti-BCMA (7A12) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human 7A12 Humanized scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF134 Anti-BCMA (7A12) h(CD28-CD3ζ) CAR, pCDCAR1 Human 7A12 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF135 Anti-BCMA (23F10) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human 23F10 Humanized scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet

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