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Prostate stem cell antigen (PSCA) is member of the Thy-1/Ly-6 family of glycosylphosphatidylinositol (GPI) anchored surface proteins, which localized to the cell surface, anchored by a GPI linkage. PSCA is expressed in the basal and secretory epithelial cell layers as well as neuroendocrine cells of human prostate. Besides, it expression is found in the placenta, bladder, neuroendocrine cells of the stomach and colon, and weekly in the kidneys excluding the glomeruli as well. In addition to the identification of PSCA as a prostate tumor associated protein, several other tumors have shown associations with PSCA such as pancreatic adenocarcinoma, transitional cell carcinoma, renal cell carcinoma and diffuse-type gastric cancer.
Associated Disease
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| CAT | Product Name | Target Species | Antibody Clone | Antibody Host | Receptor Construction | Vector Type | Targeting Cell Type | CAR Vector Type | Inquiry & Datasheet |
| XS-0822-YF1678 | Anti-Human PSCA (XW-758) h(CD28-CD3ζ) CAR IVT Plasmid, pCARIVT | Human | XW-758 | Human | scFv-CD28-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF1679 | Anti-Human PSCA (XW-759) h(CD28-CD3ζ) CAR IVT Plasmid, pCARIVT | Human | XW-759 | Human | scFv-CD28-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF1680 | Anti-Human PSCA (XW-760) h(CD28-CD3ζ) CAR IVT Plasmid, pCARIVT | Human | XW-760 | Humanized | scFv-CD28-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF1681 | Anti-Human PSCA (XW-761) h(CD28-CD3ζ) CAR IVT Plasmid, pCARIVT | Human | XW-761 | Humanized | scFv-CD28-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF1682 | Anti-Human PSCA (XW-762) h(CD28-CD3ζ) CAR IVT Plasmid, pCARIVT | Human | XW-762 | Mouse | scFv-CD28-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF1683 | Anti-Human PSCA (XW-763) h(CD28-CD3ζ) CAR IVT Plasmid, pCARIVT | Human | XW-763 | Mouse | scFv-CD28-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF1684 | Anti-Mouse PSCA (XW-764) m(CD28-CD3ζ) CAR IVT Plasmid, pCARIVT | Mouse | XW-764 | Human | scFv-CD28-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF1685 | Anti-Human PSCA (XW-765) h(CD28-CD3ζ) CAR IVT Plasmid, pCARIVT | Human | XW-765 | Mouse | scFv-CD28-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF1686 | Anti-Human PSCA (XW-766) h(CD28-CD3ζ) CAR IVT Plasmid, pCARIVT | Human | XW-766 | Humanized | scFv-CD28-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF1687 | Anti-Human PSCA (XW-767) h(CD28-CD3ζ) CAR IVT Plasmid, pCARIVT | Human | XW-767 | Mouse | scFv-CD28-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF1688 | Anti-Human PSCA (XW-768) h(CD28-CD3ζ) CAR IVT Plasmid, pCARIVT | Human | XW-768 | Mouse | scFv-CD28-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF2598 | Anti-Human PSCA (XW-758) h(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT | Human | XW-758 | Human | scFv-CD28-41BB-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF2599 | Anti-Human PSCA (XW-759) h(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT | Human | XW-759 | Human | scFv-CD28-41BB-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF2600 | Anti-Human PSCA (XW-760) h(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT | Human | XW-760 | Humanized | scFv-CD28-41BB-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF2601 | Anti-Human PSCA (XW-761) h(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT | Human | XW-761 | Humanized | scFv-CD28-41BB-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF2602 | Anti-Human PSCA (XW-762) h(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT | Human | XW-762 | Mouse | scFv-CD28-41BB-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF2603 | Anti-Human PSCA (XW-763) h(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT | Human | XW-763 | Mouse | scFv-CD28-41BB-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF2604 | Anti-Mouse PSCA (XW-764) m(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT | Mouse | XW-764 | Human | scFv-CD28-41BB-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF9552 | TS-IL15 SA Anti-Human PSCA scFv (XW-758) CD28-CD3ζ CAR, pCDCAR1 | Human | XW-758 | Human | 7H-YB-IL15 SA-EF1a-scFv-CD28-CD3ζ | Lentiviral vector | |||
| XS-0822-YF9961 | TS-IL15 SA Anti-Human PSCA scFv (XW-758) 41BB-CD3ζ CAR, pCDCAR1 | Human | XW-758 | Human | 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ | Lentiviral vector |
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