PSCA

Prostate stem cell antigen (PSCA) is member of the Thy-1/Ly-6 family of glycosylphosphatidylinositol (GPI) anchored surface proteins, which localized to the cell surface, anchored by a GPI linkage. PSCA is expressed in the basal and secretory epithelial cell layers as well as neuroendocrine cells of human prostate. Besides, it expression is found in the placenta, bladder, neuroendocrine cells of the stomach and colon, and weekly in the kidneys excluding the glomeruli as well. In addition to the identification of PSCA as a prostate tumor associated protein, several other tumors have shown associations with PSCA such as pancreatic adenocarcinoma, transitional cell carcinoma, renal cell carcinoma and diffuse-type gastric cancer.

Associated Disease

CAR Vector Products Product list:

Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-LC275 T cell Second 1G8 ~8kb Retroviral Human Inquiry
CAR-MZ037 T cell Third bm2B3 ~8kb Lentiviral scFv-CD28-41BB-CD3ζ Humanized Inquiry
CAR-MZ038 T cell First Ha1-4.117 ~8kb Lentiviral scFv-CD3ζ Human Inquiry
CAR-MZ039 T cell Second Ha1-4.117 ~8kb Lentiviral scFv-CD28-CD3ζ Human Inquiry
CAR-MZ040 T cell Third Ha1-4.117 ~8kb Lentiviral scFv-CD28-41BB-CD3ζ Human Inquiry
CAR-MZ091 NK cell First AM1 ~8kb Lentiviral scFv-DAP12 Human Inquiry
CAR-MZ092 NK cell First AM1 ~8kb Lentiviral scFv-CD3ζ Human Inquiry
CAR-MZ156 T cell First 7F5 ~8kb Lentiviral scFv-CD3ζ Mouse Inquiry
CAR-MZ157 T cell Second 7F5 ~8kb Lentiviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-T-1-L347-2 T cell First 8kb Lentiviral scFv-CD28 Inquiry
CAR-T-1-L347-G T cell First 8kb Lentiviral scFv-FcεRIγ Inquiry
CAR-T-1-L347-Z T cell First 8kb Lentiviral scFv-CD3ζ Inquiry
CAR-T-2-L347-2G T cell Second 8kb Lentiviral scFv-CD28-FcεRIγ Inquiry
CAR-T-2-L347-2Z T cell Second 8kb Lentiviral scFv-CD28-CD3ζ Inquiry
CAR-T-2-L347-4G T cell Second 8kb Lentiviral scFv-CD4-FcεRIγ Inquiry
CAR-T-2-L347-4Z T cell Second 8kb Lentiviral scFv-CD4-CD3ζ Inquiry
CAR-T-2-L347-8Z T cell Second 8kb Lentiviral scFv-CD8-CD3ζ Inquiry
CAR-T-2-L347-BZ T cell Second 8kb Lentiviral scFv-41BB-CD3ζ Inquiry
CAR-T-2-L347-CZ T cell Second 8kb Lentiviral scFv-b2c-CD3ζ Inquiry
CAR-T-3-L347-2BZ T cell Third 8kb Lentiviral scFv-CD28-41BB-CD3ζ Inquiry
CAR-T-3-L347-2XZ T cell Third 8kb Lentiviral scFv-CD28-OX40-CD3ζ Inquiry

CAR Viral Particles Product list:

Catalog Antibody
Clone
Packaging
System
Generation Gene
Construct
Promotor Packaging
Cell
Titer Data
sheet
Price
VP-CAR-LC758 bm2B3 Lentivirus Third scFv (bm2B3)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC759 Ha1-4.117 Lentivirus First scFv (Ha1-4.117)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC760 Ha1-4.117 Lentivirus Second scFv (Ha1-4.117)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC761 Ha1-4.117 Lentivirus Third scFv (Ha1-4.117)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC799 AM1 Lentivirus First scFv (AM1)-DAP12 CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC800 AM1 Lentivirus First scFv (AM1)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC851 7F5 Lentivirus First scFv (7F5)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC852 7F5 Lentivirus Second scFv (7F5)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-048-3343

Distributors

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Australia
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