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PD-L1

Programmed death-ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by the CD274. Programmed death-ligand 1 (PD-L1) is a 40kDa type 1 transmembrane protein that has been speculated to play a major role in suppressing the immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states. Tumoral PD-L1 expression status has been shown to be prognostic in multiple tumor types, including melanoma (MEL), renal cell carcinoma (RCC), and non–small-cell lung cancer (NSCLC).

Associated Disease
  • CAR Vector Products
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type Inquiry & Datasheet
CAR-LC282 Anti-CD274 h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human PD1-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-YF074 Anti-PD-L1 (CBL-YF021) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBL-YF021 Humanized scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF075 Anti-PD-L1 (CBL-YF021) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBL-YF021 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF098 Anti-PD-L1 (CBL-YF032) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBL-YF032 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF099 Anti-PD-L1 (CBL-YF032) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBL-YF032 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF129 Anti-PD-L1 (CBL-YF044) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBL-YF044 Humanized scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF130 Anti-PD-L1 (CBL-YF044) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBL-YF044 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF155 Anti-PD-L1 (CBL-YF048) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBL-YF048 Humanized scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF156 Anti-PD-L1 (CBL-YF048) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBL-YF048 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP108 Anti-PD-L1 h(41BB-CD3ζ) CAR, pCDCAR1 Human Humanized scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP109 Anti-PD-L1 h(CD28-CD3ζ) CAR, pCDCAR1 Human Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP258 Anti-PD-L1 (MEDI4736) h(CD28-CD3ζ) CAR, pCDCAR1 Human MEDI4736 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP259 Anti-PD-L1 (MEDI4736) h(41BB-CD3ζ) CAR, pCDCAR1 Human MEDI4736 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP260 Anti-PD-L1 (RG7446) h(CD28-CD3ζ) CAR, pCDCAR1 Human RG7446 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP261 Anti-PD-L1 (RG7446) h(41BB-CD3ζ) CAR, pCDCAR1 Human RG7446 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP262 Anti-PD-L1 (Avelumab) h(CD28-CD3ζ) CAR, pCDCAR1 Human Avelumab Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP263 Anti-PD-L1 (Avelumab) h(41BB-CD3ζ) CAR, pCDCAR1 Human Avelumab Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP264 Anti-PD-L1 (3G10) h(CD28-CD3ζ) CAR, pCDCAR1 Human 3G10 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP265 Anti-PD-L1 (3G10) h(41BB-CD3ζ) CAR, pCDCAR1 Human 3G10 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP266 Anti-PD-L1 (10A5) h(CD28-CD3ζ) CAR, pCDCAR1 Human 10A5 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP267 Anti-PD-L1 (10A5) h(41BB-CD3ζ) CAR, pCDCAR1 Human 10A5 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP268 Anti-PD-L1 (5F8) h(CD28-CD3ζ) CAR, pCDCAR1 Human 5F8 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP269 Anti-PD-L1 (5F8) h(41BB-CD3ζ) CAR, pCDCAR1 Human 5F8 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP270 Anti-PD-L1 (10H10) h(CD28-CD3ζ) CAR, pCDCAR1 Human 10H10 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP292 Anti-PD-L1 (2.7A4) h(CD28-CD3ζ) CAR, pCDCAR1 Human 2.7A4 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP293 Anti-PD-L1 (2.7A4) h(41BB-CD3ζ) CAR, pCDCAR1 Human 2.7A4 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP294 Anti-PD-L1 (2.9D10) h(CD28-CD3ζ) CAR, pCDCAR1 Human 2.9D10 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP295 Anti-PD-L1 (2.9D10) h(41BB-CD3ζ) CAR, pCDCAR1 Human 2.9D10 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP296 Anti-PD-L1 (2.14H9) h(CD28-CD3ζ) CAR, pCDCAR1 Human 2.14H9 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP297 Anti-PD-L1 (2.14H9) h(41BB-CD3ζ) CAR, pCDCAR1 Human 2.14H9 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP298 Anti-PD-L1 (2.20A8) h(CD28-CD3ζ) CAR, pCDCAR1 Human 2.20A8 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP299 Anti-PD-L1 (2.20A8) h(41BB-CD3ζ) CAR, pCDCAR1 Human 2.20A8 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP300 Anti-PD-L1 (3.15G8) h(CD28-CD3ζ) CAR, pCDCAR1 Human 3.15G8 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP301 Anti-PD-L1 (3.15G8) h(41BB-CD3ζ) CAR, pCDCAR1 Human 3.15G8 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP302 Anti-PD-L1 (3.18G1) h(CD28-CD3ζ) CAR, pCDCAR1 Human 3.18G1 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP303 Anti-PD-L1 (3.18G1) h(41BB-CD3ζ) CAR, pCDCAR1 Human 3.18G1 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP304 Anti-PD-L1 (2.7A40PT) h(CD28-CD3ζ) CAR, pCDCAR1 Human 2.7A40PT Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP305 Anti-PD-L1 (2.7A40PT) h(41BB-CD3ζ) CAR, pCDCAR1 Human 2.7A40PT Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP306 Anti-PD-L1 (2.14H90PT) h(CD28-CD3ζ) CAR, pCDCAR1 Human 2.14H90PT Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP307 Anti-PD-L1 (2.14H90PT) h(41BB-CD3ζ) CAR, pCDCAR1 Human 2.14H90PT Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet

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