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Programmed death-ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by the CD274. Programmed death-ligand 1 (PD-L1) is a 40kDa type 1 transmembrane protein that has been speculated to play a major role in suppressing the immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states. Tumoral PD-L1 expression status has been shown to be prognostic in multiple tumor types, including melanoma (MEL), renal cell carcinoma (RCC), and non–small-cell lung cancer (NSCLC).
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| CAT | Product Name | Target Species | Antibody Clone | Antibody Host | Receptor Construction | Vector Type | Targeting Cell Type | CAR Vector Type | Inquiry & Datasheet |
| XS-0123-ZP465 | Anti-PD-L1 (10F. 9G2) h(scFv-CD3ε) TRuC, pCDTRC1 | Mouse | 10F. 9G2 | Rat | scFv-CD3ε | Lentiviral vector | T cell | ||
| XS-0323-LX636 | Anti-PD-L1 VHH(X3XH267) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Vector | Human | X3XH267 | VHH-ICOS-4-1BB-CD3ζ | Lentiviral vector | T cell | CAR-T | ||
| XS-0323-LX637 | Anti-PD-L1 VHH(X3XH268) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Vector | Human | X3XH268 | VHH-ICOS-4-1BB-CD3ζ | Lentiviral vector | T cell | CAR-T | ||
| XS-0323-LX638 | Anti-PD-L1 VHH(X3XH269) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Vector | Human | X3XH269 | VHH-ICOS-4-1BB-CD3ζ | Lentiviral vector | T cell | CAR-T | ||
| XS-0323-LX639 | Anti-PD-L1 VHH(X3XH270) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Vector | Human | X3XH270 | VHH-ICOS-4-1BB-CD3ζ | Lentiviral vector | T cell | CAR-T | ||
| XS-0323-LX640 | Anti-PD-L1 VHH(X3XH271) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Vector | Human | X3XH271 | VHH-ICOS-4-1BB-CD3ζ | Lentiviral vector | T cell | CAR-T | ||
| XS-0323-LX641 | Anti-PD-L1 VHH(X3XH272) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Vector | Human | X3XH272 | VHH-ICOS-4-1BB-CD3ζ | Lentiviral vector | T cell | CAR-T | ||
| XS-0323-LX642 | Anti-PD-L1 VHH(X3XH273) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Vector | Human | X3XH273 | VHH-ICOS-4-1BB-CD3ζ | Lentiviral vector | T cell | CAR-T | ||
| XS-0323-LX643 | Anti-PD-L1 VHH(X3XH274) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Vector | Human | X3XH274 | VHH-ICOS-4-1BB-CD3ζ | Lentiviral vector | T cell | CAR-T | ||
| XS-0323-LX644 | Anti-PD-L1 VHH(X3XH275) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Vector | Human | X3XH275 | VHH-ICOS-4-1BB-CD3ζ | Lentiviral vector | T cell | CAR-T | ||
| XS-0323-LX1005 | Anti-PD-L1 VHH(X3XH267) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Vector | Human | X3XH267 | VHH-CD28-OX40-CD3ζ | Lentiviral vector | T cell | CAR-T | ||
| XS-0323-LX1006 | Anti-PD-L1 VHH(X3XH268) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Vector | Human | X3XH268 | VHH-CD28-OX40-CD3ζ | Lentiviral vector | T cell | CAR-T | ||
| XS-0323-LX1007 | Anti-PD-L1 VHH(X3XH269) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Vector | Human | X3XH269 | VHH-CD28-OX40-CD3ζ | Lentiviral vector | T cell | CAR-T | ||
| XS-0323-LX1008 | Anti-PD-L1 VHH(X3XH270) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Vector | Human | X3XH270 | VHH-CD28-OX40-CD3ζ | Lentiviral vector | T cell | CAR-T | ||
| XS-0323-LX1009 | Anti-PD-L1 VHH(X3XH271) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Vector | Human | X3XH271 | VHH-CD28-OX40-CD3ζ | Lentiviral vector | T cell | CAR-T | ||
| XS-0323-LX1010 | Anti-PD-L1 VHH(X3XH272) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Vector | Human | X3XH272 | VHH-CD28-OX40-CD3ζ | Lentiviral vector | T cell | CAR-T | ||
| XS-0323-LX1011 | Anti-PD-L1 VHH(X3XH273) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Vector | Human | X3XH273 | VHH-CD28-OX40-CD3ζ | Lentiviral vector | T cell | CAR-T | ||
| XS-0323-LX1012 | Anti-PD-L1 VHH(X3XH274) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Vector | Human | X3XH274 | VHH-CD28-OX40-CD3ζ | Lentiviral vector | T cell | CAR-T | ||
| XS-0323-LX1013 | Anti-PD-L1 VHH(X3XH275) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Vector | Human | X3XH275 | VHH-CD28-OX40-CD3ζ | Lentiviral vector | T cell | CAR-T | ||
| XS-0323-LX1014 | Anti-PD-L1 VHH(X3XH276) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Vector | Human | X3XH276 | VHH-CD28-OX40-CD3ζ | Lentiviral vector | T cell | CAR-T | ||
| XS-0823-LX83 | Anti-hPD-L1 (736) ICD(CD28-OX40-CD3ζ) CAR-MA, pAd5f35 Vector | Human | 736 | Adenoviral vectors |
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CellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.
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