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VEGFR-2

Vascular endothelial growth factor receptor 2 (VEGFR2) is a primary responder to vascular endothelial growth factor signal, and thereby regulates endothelial migration and proliferation. This receptor is expressed in endothelial cells and some vascular tumors, but many reports also detail its expression in carcinomas and lymphomas. VEGFR2 is a potential cell type marker, and data on VEGFR2 expression may also have therapeutic significance in view of recent availability of VEGFR2 inhibitors. As it directly upregulates tumor angiogenesis, VEGFR-2 is an appropriate target for suppression of solid tumor growth using exogenous antibodies, small inhibitory molecules and in vivo stimulation of the immune system.

Associated Disease
  • CAR Vector Products
  • CAR Viral Particles
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CAT Product Name Target SpeciesAntibody CloneAntibody HostReceptor ConstructionVector TypeTargeting Cell Type Inquiry & Datasheet
CAR-T-1-L341-2 Anti-VEGFR-2 scFv m(CD28) CART, pCDCAR1 Mouse DC101 Rat scFv-CD28 Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-L341-G Anti-VEGFR-2 scFv m(FcεRIγ) CART, pCDCAR1 Mouse DC101 Rat scFv-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-L341-Z Anti-VEGFR-2 scFv m(CD3ζ) CART, pCDCAR1 Mouse DC101 Rat scFv-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-L341-2G Anti-VEGFR-2 scFv m(CD28-FcεRIγ) CART, pCDCAR1 Mouse DC101 Rat scFv-CD28-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-L341-2Z Anti-VEGFR-2 scFv m(CD28-CD3ζ) CART, pCDCAR1 Mouse DC101 Rat scFv-CD28-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-L341-4G Anti-VEGFR-2 scFv m(CD4-FcεRIγ) CART, pCDCAR1 Mouse DC101 Rat scFv-CD4-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-L341-4Z Anti-VEGFR-2 scFv m(CD4-CD3ζ) CART, pCDCAR1 Mouse DC101 Rat scFv-CD4-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-L341-8Z Anti-VEGFR-2 scFv m(CD8-CD3ζ) CART, pCDCAR1 Mouse DC101 Rat scFv-CD8-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-L341-BZ Anti-VEGFR-2 scFv m(41BB-CD3ζ) CART, pCDCAR1 Mouse DC101 Rat scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-L341-CZ Anti-VEGFR-2 scFv m(b2c-CD3ζ) CART, pCDCAR1 Mouse DC101 Rat scFv-b2c-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-3-L341-2BZ Anti-VEGFR-2 scFv m(CD28-41BB-CD3ζ) CART, pCDCAR1 Mouse DC101 Rat scFv-CD28-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-3-L341-2XZ Anti-VEGFR-2 scFv m(CD28-OX40-CD3ζ) CART, pCDCAR1 Mouse DC101 Rat scFv-CD28-OX40-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC132 Anti-VEGFR-2 (KDR-1121) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human KDR-1121 Human scFv-CD28-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC133 Anti-VEGFR-2 (KDR-1121) h(CD28-CD3ζ) CAR, pCDCAR1 Human KDR-1121 Human scFv-CD28-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-ZP055 Anti-VEGFR-2 (AB1) h(41BB-CD3ζ) CAR, pCDCAR1 Human AB1 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP062 Anti-VEGFR-2 (KDR D1-7) h(41BB-CD3ζ) CAR, pCDCAR1 Human KDR D1-7 Camelidae scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP063 Anti-VEGFR-2 (KDR D1-7) h(CD28-CD3ζ) CAR, pCDCAR1 Human KDR D1-7 Camelidae scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP029 Anti-VEGFR-2 (AB1) h(CD28-CD3ζ) CAR, pCDCAR1 Human AB1 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet

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