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ALK

Anaplastic lymphoma kinase (ALK) also known as ALK tyrosine kinase receptor or CD246, is an enzyme that in humans is encoded by the ALK gene. ALK is a membrane associated tyrosine kinase receptor of the insulin receptor superfamily. The function of the full-length ALK receptor is poorly understood. It has a probable role in the central and peripheral nervous system development and maintenance. ALK is a dependence receptor, which may exert antagonist functions, proapoptotic or antiapoptotic, depending on the absence or presence of a ligand. Dependence receptors have a potential role in cancer and development. The EML4-ALK fusion gene is responsible for approximately 3-5% of non-small-cell lung cancer(NSCLC) and this gene product was designed for the treatment of NSCLC.

Associated Disease
  • Non-small cell lung cancer (NSCLC)
  • Anaplastic large cell lymphoma (ALCL)
  • Diffuse large B-cell lymphoma (DLBCL)
  • Lung malignancy
  • CAR Vector Products
  • CAR Viral Particles
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  • Antibody Clone:
  • Antibody Host:
  • Receptor Construction:
CAT Product Name Target SpeciesAntibody CloneAntibody HostReceptor ConstructionVector TypeTargeting Cell Type Inquiry & Datasheet
CAR-LC101 Anti-ALK (ALK15) h(CD28-CD3ζ) CAR, pCDCAR1 Human ALK15 Mouse scFv-CD28-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC102 Anti-ALK (ALK15) h(41BB-CD3ζ) CAR, pCDCAR1 Human ALK15 Mouse scFv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC103 Anti-ALK (ALK15) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human ALK15 Mouse scFv-CD28-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC104 Anti-ALK (hALK15SH) h(CD28-CD3ζ) CAR, pCDCAR1 Human hALK15SH Human scFv-CD28-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC105 Anti-ALK (hALK15SH) h(41BB-CD3ζ) CAR, pCDCAR1 Human hALK15SH Human scFv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC106 Anti-ALK (hALK15SH) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human hALK15SH Human scFv-CD28-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC107 Anti-ALK (ALK48) h(CD28-CD3ζ) CAR, pCDCAR1 Human ALK48 Mouse scFv-CD28-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC108 Anti-ALK (ALK48) h(41BB-CD3ζ) CAR, pCDCAR1 Human ALK48 Mouse scFv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC109 Anti-ALK (ALK48) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human ALK48 Mouse scFv-CD28-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC110 Anti-ALK (hALK48SH) h(CD28-CD3ζ) CAR, pCDCAR1 Human hALK48SH Human scFv-CD28-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC111 Anti-ALK (hALK48SH) h(41BB-CD3ζ) CAR, pCDCAR1 Human hALK48SH Human scFv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC112 Anti-ALK (hALK48SH) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human hALK48SH Human scFv-CD28-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC113 Anti-ALK (ALK53) h(CD28-CD3ζ) CAR, pCDCAR1 Human ALK53 Mouse scFv-CD28-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC114 Anti-ALK (ALK53) h(41BB-CD3ζ) CAR, pCDCAR1 Human ALK53 Mouse scFv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC115 Anti-ALK (ALK53) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human ALK53 Mouse scFv-CD28-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC116 Anti-ALK (hALK53) h(CD28-CD3ζ) CAR, pCDCAR1 Human hALK53 Human scFv-CD28-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC117 Anti-ALK (hALK53) h(41BB-CD3ζ) CAR, pCDCAR1 Human hALK53 Human scFv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC118 Anti-ALK (hALK53) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human hALK53 Human scFv-CD28-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC119 Anti-ALK (ALK58) h(CD28-CD3ζ) CAR, pCDCAR1 Human ALK58 Mouse scFv-CD28-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC120 Anti-ALK (ALK58) h(41BB-CD3ζ) CAR, pCDCAR1 Human ALK58 Mouse scFv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC121 Anti-ALK (ALK58) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human ALK58 Mouse scFv-CD28-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC122 Anti-ALK (hALK58) h(CD28-CD3ζ) CAR, pCDCAR1 Human hALK58 Human scFv-CD28-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC123 Anti-ALK (hALK58) h(41BB-CD3ζ) CAR, pCDCAR1 Human hALK58 Human scFv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC124 Anti-ALK (hALK58) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human hALK58 Human scFv-CD28-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet

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