shRNA Adenovirus Serotype 5 (ΔE1/E3), p7SK-(Hsp7SK-shRNA-Seq5)(CAT#: AdV-SI3669WQ)

This product is a Hsph1-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The Hsph1 gene encodes a member of the heat shock protein 70 family of proteins and functions as a nucleotide exchange factor for the molecular chaperone heat shock cognate 71 kDa protein (Hsc70). The expression of Hsph1-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Adenoviridae
Species Adenovirus
Serotype AdV-5
Backbone AdV-5 (ΔE1/E3)
Tropism Both nondividing and dividing cells
Modification ΔE1/E3
Insert Hsph1-shRNA-Seq5
Related Target/Protein Hsph1
Region CDS
TargetSeq GACCTTCTTAACATGTATATT
NCBI RefSeq NM_013559
Alternative Names HSP105; HSP105A; HSP105B; NY-CO-25
Titer >1*10^10 GC/mL
Related Diseases Cancer
Target Gene
Gene ID 10808
Uniprot ID Q92598

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