shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(OR8D4-shRNA-Seq2)(CAT#: AdV-SI1593WQ)

This product is a OR8D4-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The OR8D4 gene encodes a olfactory receptor protein that interacts with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The expression of OR8D4-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Adenoviridae
Species Adenovirus
Serotype AdV-5
Backbone AdV-5 (ΔE1/E3)
Tropism Both nondividing and dividing cells
Modification ΔE1/E3
Insert OR8D4-shRNA-Seq2
Related Target/Protein OR8D4
Region CDS
TargetSeq CCTCAGCATGATCTCAATTAT
NCBI RefSeq XM_291838
Alternative Names OR11-275
Titer >1*10^10 GC/mL
Related Diseases Olfactory dysfunction
Target Gene
Gene ID 338662
Uniprot ID Q8NGM9

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