shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(PRM2-shRNA-Seq3)(CAT#: AdV-SI0397WQ)

This product is a PRM2-shRNA encoding AdV, which is based on AdV-5 serotype with EIB-55K gene deleted. The PRM2 gene encodes protamine 2, which is cleaved to give rise to a family of protamine 2 peptides. The expression of PRM2-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Adenoviridae
Species Adenovirus
Serotype HAdV-5
Backbone AdV-5 (ΔE1/E3)
Tropism Both nondividing and dividing cells
Insert PRM2-shRNA-Seq3
Related Target/Protein PRM2
Region CDS
TargetSeq GAAGAGAACATGCAGAAGGCA
NCBI RefSeq NM_002762
Alternative Names CT94.2
Titer >1*10^10 GC/mL
Related Diseases Prostate cancer
Target Gene
Gene ID 5620
Uniprot ID P04554

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