shRNA Lentivirus (self-inactivating), pH1-(C12orf48-shRNA-Seq2)(CAT#: LV-SI0774WQ)

This product is a C12orf48-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The C12orf48 is required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability. The expression of C12orf48-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Retroviridae
Species Lentivirus
Serotype HIV-1
Backbone Lenti-SIN
Tropism Both nondividing and dividing cells
Insert C12orf48-shRNA-Seq2
Related Target/Protein C12orf48
Region CDS
TargetSeq GAGGGTGTAAATCCATCTGTT
NCBI RefSeq NM_017915
Alternative Names AROM; PARI; PARPBP
Titer >1*10^10 GC/mL
Related Diseases Hepatocellular Carcinoma
Target Gene
Gene ID 55010
Uniprot ID Q9NWS1

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