shRNA Adeno-associated Virus Serotype 2, p7SK-(LAMP3-shRNA-Seq2)(CAT#: AAV-SI1242WQ)

This product is a LAMP3-shRNA encoding AAV, which is based on AAV-2 serotype. LAMP3 regulates hepatic lipid metabolism through activating PI3K/Akt pathway. LAMP3 promotes the invasion of osteosarcoma cells via SPP1 signaling. LAMP3 expression correlated with poor clinical outcome in human ovarian cancer. The expression of LAMP3-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.