shRNA Adeno-associated Virus Serotype 2, pH1-(Bcdin3d-shRNA-Seq1)(CAT#: AAV-SI3100WQ)
This product is a Bcdin3d-shRNA encoding AAV, which is based on AAV-2 serotype. The Bcdin3d gene encodes an RNA methyltransferase which belongs to the rossmann fold methyltransferase family, and serves as a 5'-methylphosphate capping enzyme that is specific for cytoplasmic histidyl tRNA. The expression of Bcdin3d-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
| Specifications | |
|---|---|
| Family | Parvoviridae |
| Species | Adeno-associated virus (AAV) |
| Serotype | AAV-2 |
| Backbone | AAV-2 |
| Tropism | CNS, muscle, liver, brain, eye |
| Insert | Bcdin3d-shRNA-Seq1 |
| Related Target/Protein | Bcdin3d |
| Region | CDS |
| TargetSeq | CTCTGTACAAACATTTCCTTT |
| NCBI RefSeq | NM_029236 |
| Titer | >1*10^10 GC/mL |
| Related Diseases | Breast cancer |