shRNA Adeno-associated Virus Serotype 2, pH1-(SH3D19-shRNA-Seq2)(CAT#: AAV-SI0778WQ)

This product is a SH3D19-shRNA encoding AAV, which is based on AAV-2 serotype. The SH3D19 gene encoded protein may be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1 by EBP, and regulation of ADAM proteins in the signaling of EGFR-ligand shedding. The expression of SH3D19-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.