shRNA Adeno-associated Virus Serotype 2, pU6-(JMJD8-shRNA-Seq1)(CAT#: AAV-SI0153WQ)

This product is a JMJD8-shRNA encoding AAV, which is based on AAV-2 serotype. The JMJD8 gene functions as a positive regulator of TNF-induced NF-kappa-B signaling and regulates angiogenesis and cellular metabolism through interaction with PKM. The expression of JMJD8-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.