siRNA, Anti-PADI1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT76581WQ-2OMe)

The product SIRGT76581WQ-2OMe is a type of small interfering RNA (siRNA) that targets PADI1 gene and regulates the expression of gene. The siRNA interferes with the expression of PADI1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_013358.2
Alternative Names HPAD10; PAD1; PDI; PDI1
Related Diseases Myopathy, Distal, 1.
Purification HPLC
Target Gene
Gene ID 29943
Uniprot ID Q9ULC6
Sub Cat Target Species Modification Scale  
SIRGT77581WQ-2F PADI1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT78581WQ-2MOE PADI1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT79581WQ-LNA PADI1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT76581WQ-RB PADI1 Human Ribo-modified Inquiry
SIRGT77581WQ-BB PADI1 Human Backbone-modified Inquiry

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