siRNA, Anti-PAQR8, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT51208WQ-2OMe)

The product SIRGT51208WQ-2OMe is a type of small interfering RNA (siRNA) that targets PAQR8 gene and regulates the expression of gene. The siRNA interferes with the expression of PAQR8 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_133367.4
Alternative Names C6orf33; LMPB1; MPRB
Related Diseases Epilepsy With Generalized Tonic-Clonic Seizures
Purification HPLC
Target Gene
Gene ID 85315
Uniprot ID Q8TEZ7
Sub Cat Target Species Modification Scale  
SIRGT52208WQ-2F PAQR8 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT53208WQ-2MOE PAQR8 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT54208WQ-LNA PAQR8 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT51208WQ-RB PAQR8 Human Ribo-modified Inquiry
SIRGT52208WQ-BB PAQR8 Human Backbone-modified Inquiry

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