siRNA, Anti-ABCA2, 2'-F/2'-MOE/LNA/Backbone-modified(CAT#: SIRGT02012WQ-2F)

The product SIRGT02012WQ-2F is a type of small interfering RNA (siRNA) that targets ABCA2 gene and regulates the expression of gene. The siRNA interferes with the expression of ABCA2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-deoxy-2ʹ-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001606.4; NM_212533.2
Alternative Names ABC2
Related Diseases Macrophage lipid metabolism and neural development
Purification HPLC
Target Gene
Gene ID 20
Uniprot ID Q9BZC7
Sub Cat Target Species Modification Scale  
SIRGT03012WQ-2MOE ABCA2 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04012WQ-LNA ABCA2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT02012WQ-BB ABCA2 Human Backbone-modified Inquiry

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