siRNA, Anti-ALPI, 2'-F/2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT01162WQ-2OMe)

The product SIRGT01162WQ-2OMe is a type of small interfering RNA (siRNA) that targets ALPI gene and regulates the expression of gene. The siRNA interferes with the expression of ALPI gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001631.4
Alternative Names IAP
Related Diseases Hypophosphatasia, Granulomatous Hepatitis
Purification HPLC
Target Gene
Gene ID 248
Uniprot ID P09923
Sub Cat Target Species Modification Scale  
SIRGT02162WQ-2F ALPI Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT04162WQ-LNA ALPI Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01162WQ-RB ALPI Human Ribo-modified Inquiry
SIRGT02162WQ-BB ALPI Human Backbone-modified Inquiry

Related Products