siRNA, Anti-ANG, 2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT03183WQ-2MOE)

The product SIRGT03183WQ-2MOE is a type of small interfering RNA (siRNA) that targets ANG gene and regulates the expression of gene. The siRNA interferes with the expression of ANG gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2'-O-methoxyethyl (2'-MOE) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001097577.2; NM_001145.4
Alternative Names ALS9; HEL168; RAA1; RNASE4; RNASE5
Related Diseases Amyotrophic Lateral Sclerosis
Purification HPLC
Target Gene
Gene ID 283
Uniprot ID P01019
Sub Cat Target Species Modification Scale  
SIRGT04183WQ-LNA ANG Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01183WQ-RB ANG Human Ribo-modified Inquiry
SIRGT02183WQ-BB ANG Human Backbone-modified Inquiry

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