siRNA, Anti-AQP6, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01246WQ-2OMe)

The product SIRGT01246WQ-2OMe is a type of small interfering RNA (siRNA) that targets AQP6 gene and regulates the expression of gene. The siRNA interferes with the expression of AQP6 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001652.3
Alternative Names AQP2L; KID
Related Diseases Meniere Disease, Acoustic Neuroma
Purification HPLC
Target Gene
Gene ID 363
Uniprot ID Q13520
Sub Cat Target Species Modification Scale  
SIRGT02246WQ-2F AQP6 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03246WQ-2MOE AQP6 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04246WQ-LNA AQP6 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01246WQ-RB AQP6 Human Ribo-modified Inquiry
SIRGT02246WQ-BB AQP6 Human Backbone-modified Inquiry

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