siRNA, Anti-ATP4B, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01334WQ-2OMe)

The product SIRGT01334WQ-2OMe is a type of small interfering RNA (siRNA) that targets ATP4B gene and regulates the expression of gene. The siRNA interferes with the expression of ATP4B gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000705.3
Alternative Names ATP6B
Related Diseases Myasthenic Syndrome, Gastric Adenocarcinoma
Purification HPLC
Target Gene
Gene ID 496
Uniprot ID P51164
Sub Cat Target Species Modification Scale  
SIRGT02334WQ-2F ATP4B Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03334WQ-2MOE ATP4B Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04334WQ-LNA ATP4B Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01334WQ-RB ATP4B Human Ribo-modified Inquiry
SIRGT02334WQ-BB ATP4B Human Backbone-modified Inquiry

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