siRNA, Anti-BNIP3, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01443WQ-2OMe)

The product SIRGT01443WQ-2OMe is a type of small interfering RNA (siRNA) that targets BNIP3 gene and regulates the expression of gene. The siRNA interferes with the expression of BNIP3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_004052.3
Alternative Names NIP3
Related Diseases Hereditary Leiomyomatosis, Renal Cell Cancer and Leiomyomatosis
Purification HPLC
Target Gene
Gene ID 664
Uniprot ID Q12983
Sub Cat Target Species Modification Scale  
SIRGT02443WQ-2F BNIP3 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03443WQ-2MOE BNIP3 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04443WQ-LNA BNIP3 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01443WQ-RB BNIP3 Human Ribo-modified Inquiry
SIRGT02443WQ-BB BNIP3 Human Backbone-modified Inquiry

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