siRNA, Anti-BSG, 2'-F/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT02458WQ-2F)
The product SIRGT02458WQ-2F is a type of small interfering RNA (siRNA) that targets BSG gene and regulates the expression of gene. The siRNA interferes with the expression of BSG gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-deoxy-2ʹ-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001322243.1; NM_001728.3; NM_198589.2; NM_198590.2; NM_198591.2 |
| Alternative Names | 5F7; CD147; EMMPRIN; OK; TCSF |
| Related Diseases | Adult Brain Stem Glioma, Ameloblastoma |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT03458WQ-2MOE | BSG | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT04458WQ-LNA | BSG | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT01458WQ-RB | BSG | Human | Ribo-modified | ||
| SIRGT02458WQ-BB | BSG | Human | Backbone-modified |