siRNA, Anti-CLCN1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01814WQ-2OMe)

The product SIRGT01814WQ-2OMe is a type of small interfering RNA (siRNA) that targets CLCN1 gene and regulates the expression of gene. The siRNA interferes with the expression of CLCN1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000083.2
Alternative Names CLC1
Related Diseases Myotonia Congenita
Purification HPLC
Target Gene
Gene ID 1180
Uniprot ID P35523
Sub Cat Target Species Modification Scale  
SIRGT02814WQ-2F CLCN1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03814WQ-2MOE CLCN1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04814WQ-LNA CLCN1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01814WQ-RB CLCN1 Human Ribo-modified Inquiry
SIRGT02814WQ-BB CLCN1 Human Backbone-modified Inquiry

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