siRNA, Anti-COL14A1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21837WQ-2OMe)

The product SIRGT21837WQ-2OMe is a type of small interfering RNA (siRNA) that targets COL14A1 gene and regulates the expression of gene. The siRNA interferes with the expression of COL14A1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_021110.3
Alternative Names UND
Related Diseases Punctate Palmoplantar Keratoderma
Purification HPLC
Target Gene
Gene ID 7373
Uniprot ID Q05707
Sub Cat Target Species Modification Scale  
SIRGT22837WQ-2F COL14A1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23837WQ-2MOE COL14A1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24837WQ-LNA COL14A1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21837WQ-RB COL14A1 Human Ribo-modified Inquiry
SIRGT22837WQ-BB COL14A1 Human Backbone-modified Inquiry

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