siRNA, Anti-COQ5, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT46873WQ-2OMe)

The product SIRGT46873WQ-2OMe is a type of small interfering RNA (siRNA) that targets COQ5 gene and regulates the expression of gene. The siRNA interferes with the expression of COQ5 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_032314.3
Related Diseases Coenzyme Q10 Deficiency Disease
Purification HPLC
Target Gene
Gene ID 84274
Uniprot ID Q5HYK3
Sub Cat Target Species Modification Scale  
SIRGT47873WQ-2F COQ5 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT48873WQ-2MOE COQ5 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT49873WQ-LNA COQ5 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT46873WQ-RB COQ5 Human Ribo-modified Inquiry
SIRGT47873WQ-BB COQ5 Human Backbone-modified Inquiry

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