siRNA, Anti-DHCR24, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT06145WQ-2OMe)

The product SIRGT06145WQ-2OMe is a type of small interfering RNA (siRNA) that targets DHCR24 gene and regulates the expression of gene. The siRNA interferes with the expression of DHCR24 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_014762.3
Alternative Names DCE; Nbla03646; SELADIN1; seladin-1
Related Diseases Desmosterolosis, Alzheimer Disease
Purification HPLC
Target Gene
Gene ID 1718
Uniprot ID Q15392
Sub Cat Target Species Modification Scale  
SIRGT07145WQ-2F DHCR24 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08145WQ-2MOE DHCR24 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT06145WQ-RB DHCR24 Human Ribo-modified Inquiry
SIRGT07145WQ-BB DHCR24 Human Backbone-modified Inquiry

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