siRNA, Anti-UQCR11, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT36210WQ-2OMe)

The product SIRGT36210WQ-2OMe is a type of small interfering RNA (siRNA) that targets UQCR11 gene and regulates the expression of gene. The siRNA interferes with the expression of UQCR11 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_006830.3
Alternative Names 0710008D09Rik; QCR10; UQCR
Related Diseases Gracile Syndrome
Purification HPLC
Target Gene
Gene ID 10975
Uniprot ID O14957
Sub Cat Target Species Modification Scale  
SIRGT37210WQ-2F UQCR11 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT38210WQ-2MOE UQCR11 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT39210WQ-LNA UQCR11 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT36210WQ-RB UQCR11 Human Ribo-modified Inquiry
SIRGT37210WQ-BB UQCR11 Human Backbone-modified Inquiry

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