siRNA, Anti-VDAC1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21868WQ-2OMe)

The product SIRGT21868WQ-2OMe is a type of small interfering RNA (siRNA) that targets VDAC1 gene and regulates the expression of gene. The siRNA interferes with the expression of VDAC1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_003374.2
Alternative Names PORIN; VDAC-1
Related Diseases Influenza, Typhoid Fever
Purification HPLC
Target Gene
Gene ID 7416
Uniprot ID P21796
Sub Cat Target Species Modification Scale  
SIRGT22868WQ-2F VDAC1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23868WQ-2MOE VDAC1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24868WQ-LNA VDAC1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21868WQ-RB VDAC1 Human Ribo-modified Inquiry
SIRGT22868WQ-BB VDAC1 Human Backbone-modified Inquiry

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