Targeted CD117 Ab-LNP

Cat. No.: TDLD-0825-LD69

Targeted CD117 Ab-LNP

Targeted CD117 Ab-LNP is a state-of-the-art antibody-functionalized lipid nanoparticle (LNP), designed for targeted delivery of therapeutic cargoes such as siRNA, mRNA, DNA, small molecule drugs, and RNA-guided gene editing systems. Engineered with the CD34 antibody, this LNP specifically recognizes and binds to the CD117 receptor, a key growth factor receptor expressed on hematopoietic stem cells, mast cells, germ cells, and various tumor cell types, facilitating selective internalization into these CD117-positive cells. The LNPs can be supplied in an empty state, or pre-loaded with a variety of optimized mRNA molecules featuring capping and other modifications to enhance stability and expression. Our LNP is allows for the optional lipid formulations including DLin-MC3-DMA, LP-01, ALC-0315, SM102, and others, ensuring exceptional performance characterized by uniform particle size, high encapsulation efficiency, robust stability, and potent cellular uptake. Applications of Targeted CD34 Ab-LNP include investigating stem cell and mast cell biology and serving as a versatile platform for delivering nucleic acid payloads specifically to CD117-expressing cells. Please note that this product is intended for research purposes only.