One-Stop Targeted Drug Delivery Platform

Our integrated platform is meticulously designed to overcome the inherent challenges of therapeutic targeting, ensuring that your valuable cargo reaches its intended destination with exceptional specificity and efficacy. We leverage a synergistic approach, combining advanced delivery systems/drugs with sophisticated targeting modules, to unlock new possibilities in medicine.

Creative Biolabs' One-Stop Targeted Drug Delivery Platform

Selective Organ Targeting (SORT) LNP Development

Advanced lipid nanoparticle (LNP) formulation and optimization for precise delivery to specific organs and tissues.

Integrated Small Molecule Delivery System Development

Comprehensive solutions for enhancing the bioavailability and targeted delivery of small molecule therapeutics.

In Vitro Characterization & Assay Development

Robust analytical and biological assays to thoroughly characterize delivery systems and assess their efficacy and safety.

In Vivo PK/PD & Biodistribution Studies

Expert design and execution of in vivo studies to evaluate drug distribution, metabolism, and therapeutic effects.

Bioconjugation & Functionalization Platform

Our specialized platform for the precise chemical conjugates and functionalization of delivery systems with targeting modules.

IND-Enabling Studies & GMP Manufacturing Support

Guidance and support through the critical stages of Investigational New Drug (IND) application, including Good Manufacturing Practice (GMP) compliant manufacturing strategies.

Click the Video to Learn More about Liposomal Delivery Systems in Cancer Therapy

What Drug Do You Want to Deliver?

Creative Biolabs offers comprehensive delivery solutions tailored for a wide spectrum of drugs, ensuring optimal performance regardless.

Prolonged Half-life
Enhanced Stability
Improved Targeting Precision
Increased Membrane Permeability
Protection of Bioactivity

Small molecule

Enzyme

Protein Peptide

DNA

mRNA

siRNA

MicroRNA

ASO

Virus

CRISPR-Cas9

Probe

Plasmid

Strategically Selected Module Delivery Systems

Our modular approach integrates a diverse array of advanced delivery systems, including liposomes, exosomes, LNPs, and more. Each system is carefully designed and optimized to ensure efficient drug loading, protection, and release.

Liposomes

Versatile lipid-based vesicles offering excellent biocompatibility and capacity for encapsulating both hydrophilic and hydrophobic drugs.

Lipid Nanoparticles (LNP)

Advanced lipid-based delivery systems, particularly effective for nucleic acids like mRNA, providing stability and efficient cellular uptake.

Exosomes

Naturally occurring nanovesicles with inherent targeting capabilities and low immunogenicity, ideal for biological cargo and cell-to-cell communication.

Virus-Like Particles (VLP)

Non-replicating, self-assembling protein structures that mimic viruses, offering robust delivery potential for various payloads.

Micelles

Self-assembling systems formed by amphiphilic molecules, suitable for hydrophobic drug encapsulation and improved systemic circulation.

Hydrogels

Three-dimensional polymeric networks capable of absorbing large amounts of water, offering controlled release and localized delivery.

Precisely Engineered Targeting Modules

To achieve unparalleled specificity, we employ a sophisticated array of targeting modules that guide our delivery systems to their intended cellular or tissue targets.

Antibody

Proteins

Peptides

Aptamer

Polymer

Advanced Conjugation Capabilities

Creative Biolabs excels in the precise conjugate of therapeutic agents with our sophisticated targeting modules and delivery systems. Our advanced conjugation platform enables the creation of highly specific and potent drug conjugates, designed to maximize therapeutic efficacy while minimizing off-target effects. We offer expertise across a range of conjugation strategies.

Drug-Ligand Conjugates

DRUG PAYLOAD

LINKER SYSTEM

TARGETING LIGAND

Advanced Platform and Advantages

At Creative Biolabs, our distinction lies in our integrated, customizable, and highly advanced platform.

Integrated Modular Design

Unparalleled flexibility and precision through combining diverse delivery systems and targeting modules.

Comprehensive Characterization

Rigorous in vitro and in vivo analysis ensures safety, efficacy, and stability.

Customization and Collaboration

Tailored solutions and a collaborative approach for specific project needs.

Translational Expertise

End-to-end guidance from concept to IND-enabling studies and GMP manufacturing, streamlining development.

Commitment to Innovation

Continuous integration of the latest advancements in drug delivery technology.

Problem-Solving Focus

Dedicated to addressing complex targeting and bioavailability challenges.

Case Study: Lung Targeted LNP for mRNA Delivery

Our mature LNP platform offers efficient targeting solutions for various organs and tissues, including the brain, heart, lung, liver, spleen, muscle, and T cells. We also provide customized targeting system development services to meet specific research and clinical needs.

Fig. 1 In vivo expression and distribution of Creative Biolabs' lung-targeted mRNA-LNP in mice.

Our lung-targeted LNPs show exceptional efficiency in delivering mRNA to the lungs, offering great potential for treating respiratory diseases and conditions.

Get Targeting Data

Workflow

Advanced Platform and Advantages

What makes targeted drug delivery superior to conventional methods?

Targeted drug delivery minimizes off-target effects, reduces systemic toxicity, and increases therapeutic efficacy by concentrating the drug at the site of disease.

How does Creative Biolabs ensure the specificity of its targeting delivery systems?

We use robust design, advanced bioconjugation, and extensive in vitro and in vivo testing to confirm our targeting delivery systems precisely bind to intended sites with minimal off-target effects.

Can Creative Biolabs assist with early-stage drug discovery projects?

Yes, we support projects from initial concept through IND-enabling studies, helping identify delivery systems, targeting modules, and providing early proof-of-concept data.

Is Creative Biolabs equipped to handle various drug types?

Yes, our platform handles a wide range of drugs, from small molecules to complex biologics and novel nucleic acids (mRNA, siRNA, miRNA, ASO, plasmid DNA), adapting strategies for optimal delivery.

What kind of customization options does Creative Biolabs offer?

We offer extensive customization for delivery systems, targeting modules, conjugation strategies, and assay development, ensuring solutions are precisely aligned with your unique project needs.

Partner with Creative Biolabs to unlock the full potential of your therapeutics through precise and effective targeted drug delivery.