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Targeted CD5 Ab-LNP

Cat. No.: TDLD-0825-LD66

Targeted CD5 Ab-LNP

Targeted CD5 Ab-LNP is a state-of-the-art antibody-functionalized lipid nanoparticle (LNP), designed for targeted delivery of therapeutic cargoes such as siRNA, mRNA, DNA, small molecule drugs, and RNA-guided gene editing systems. Engineered with the CD5 antibody, this LNP specifically recognizes and binds to the CD5 receptor expressed on the surface of T cells, B-1 cells, and thymocytes, enabling selective targeting and uptake into these specific cells. The LNPs can be supplied in an empty state, or pre-loaded with a variety of optimized mRNA molecules featuring capping and other modifications to enhance stability and expression. Our LNP is allows for the optional lipid formulations including DLin-MC3-DMA, LP-01, ALC-0315, SM102, and others, ensuring exceptional performance characterized by uniform particle size, high encapsulation efficiency, robust stability, and potent cellular uptake. Applications of Targeted CD5 Ab-LNP include investigating T cell and B-1 cell biology and serving as a versatile platform for delivering nucleic acid payloads specifically to CD5-expressing cells. Please note that this product is intended for research purposes only.

SPECIFIC INQUIRY
Payload:
Modification:
Lipid Formulation:
Dye:
Concentration:
Quantity:
Inquiry
For Research Use Only. Not for Diagnostic or Treatment Applications.
Payload Type mRNA
Payload Empty; EGFP mRNA; Firefly Luciferase mRNA; mCherry mRNA; GFP mRNA; OVA mRNA; EPO mRNA; Renilla Luciferase mRNA; Gaussia Luciferase mRNA; Beta-galactosidase mRNA; Cre mRNA; mOrange mRNA; tdTomato mRNA; EYFP mRNA
Capping Cap 1
Modification Unmodified; N1-methyl-pseudouridine; 5-methoxyuridine
Module Type Antibody
Targeting Module CD5 Antibody
Target CD5⁺ Cells
Lipid Formulation DLin-MC3-DMA; LP-01; ALC-0315; SM102
Dye Unlabeled; DiR; DiD; DiO; DiI
Application Control; Targeted Delivery; Gene Therapy
Format Liquid
Concentration 0.1 mg/mL; 0.2 mg/mL; Other (Please Specify)
Size 65-120 nm
PDI < 0.2
Zeta ± 20.0 mV
Encapsulate Efficiency >90%
Storage Store at 2-8°C
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