Targeted CD5 Ab-LNP
Cat. No.: TDLD-0825-LD66
Targeted CD5 Ab-LNP
Targeted CD5 Ab-LNP is a state-of-the-art antibody-functionalized lipid nanoparticle (LNP), designed for targeted delivery of therapeutic cargoes such as siRNA, mRNA, DNA, small molecule drugs, and RNA-guided gene editing systems. Engineered with the CD5 antibody, this LNP specifically recognizes and binds to the CD5 receptor expressed on the surface of T cells, B-1 cells, and thymocytes, enabling selective targeting and uptake into these specific cells. The LNPs can be supplied in an empty state, or pre-loaded with a variety of optimized mRNA molecules featuring capping and other modifications to enhance stability and expression. Our LNP is allows for the optional lipid formulations including DLin-MC3-DMA, LP-01, ALC-0315, SM102, and others, ensuring exceptional performance characterized by uniform particle size, high encapsulation efficiency, robust stability, and potent cellular uptake. Applications of Targeted CD5 Ab-LNP include investigating T cell and B-1 cell biology and serving as a versatile platform for delivering nucleic acid payloads specifically to CD5-expressing cells. Please note that this product is intended for research purposes only.
| Payload Type | mRNA |
| Payload | Empty; EGFP mRNA; Firefly Luciferase mRNA; mCherry mRNA; GFP mRNA; OVA mRNA; EPO mRNA; Renilla Luciferase mRNA; Gaussia Luciferase mRNA; Beta-galactosidase mRNA; Cre mRNA; mOrange mRNA; tdTomato mRNA; EYFP mRNA; Others |
| Capping | Cap 1 |
| Modification | Unmodified; N1-methyl-pseudouridine; 5-methoxyuridine; Other |
| Module Type | Antibody |
| Targeting Module | CD5 Antibody |
| LNP Type | Ab-LNP; Empty LNP; mRNA-LNP |
| Target | CD5⁺ Cells |
| Lipid Formulation | DLin-MC3-DMA; LP-01; ALC-0315; SM102; Other |
| Dye | Unlabeled; DiR; DiD; DiO; DiI; Other |
| Application | Targeted Delivery; Gene Therapy |
| Format | Liquid |
| Concentration | 0.1 mg/mL; 0.2 mg/mL; Other (Please Specify) |
| Size | 65-120 nm |
| PDI | < 0.2 |
| Zeta | ± 20.0 mV |
| Encapsulate Efficiency | >90% |
| Shipping | Dry Ice |
| Storage | Store at -80°C |
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