Targeted CD34 Ab-LNP

Cat. No.: TDLD-0825-LD68

Targeted CD34 Ab-LNP

Targeted CD34 Ab-LNP is a state-of-the-art antibody-functionalized lipid nanoparticle (LNP), designed for targeted delivery of therapeutic cargoes such as siRNA, mRNA, DNA, small molecule drugs, and RNA-guided gene editing systems. Engineered with the CD34 antibody, this LNP specifically recognizes and binds to the CD34 glycoprotein, a well-established marker for HSPCs as well as endothelial progenitor cells, enabling selective targeting and internalization into these critical cell populations. The LNPs can be supplied in an empty state, or pre-loaded with a variety of optimized mRNA molecules featuring capping and other modifications to enhance stability and expression. Our LNP is allows for the optional lipid formulations including DLin-MC3-DMA, LP-01, ALC-0315, SM102, and others, ensuring exceptional performance characterized by uniform particle size, high encapsulation efficiency, robust stability, and potent cellular uptake. Applications of Targeted CD34 Ab-LNP include investigating HSPC biology and serving as a powerful tool for delivering specific mRNA payloads directly to stem and progenitor cell compartments. Please note that this product is intended for research purposes only.