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KAA Pep-LNP

Cat. No.: TDLD-0825-LD103

KAA Pep-LNP

KAA Pep-LNP is a state-of-the-art peptide-functionalized lipid nanoparticle (LNP), designed for efficient targeted delivery of therapeutic cargoes such as siRNA, mRNA, DNA, small molecule drugs, and RNA-guided gene editing systems. Engineered with the FKAA peptide, this LNP specifically recognizes and binds to unique markers expressed on pancreatic cancer cells, enabling precise localization of the therapeutic payload directly to the tumor site. Our LNP is prepared using DSPE-PEG-KAA and a variety of optional lipid formulations including DLin-MC3-DMA, LP-01, ALC-0315, SM102, and others. These formulations are carefully selected to ensure the LNP has uniform particle size, high encapsulation efficiency, stability, and targeted delivery. Applications of KAA Pep-LNP include developing highly specific pancreatic cancer therapeutics, creating targeted imaging agents for pancreatic tumors, studying the biology of pancreatic cancer cell markers, and evaluating novel strategies for selective pancreatic cancer treatment. Please note that this product is intended for research purposes only.

SPECIFIC INQUIRY
Payload:
Modification:
Lipid Formulation:
Dye:
Concentration:
Quantity:
Inquiry
For Research Use Only. Not for Diagnostic or Treatment Applications.
Payload Type mRNA
Payload Empty; EGFP mRNA; Firefly Luciferase mRNA; mCherry mRNA; GFP mRNA; OVA mRNA; EPO mRNA; Renilla Luciferase mRNA; Gaussia Luciferase mRNA; Beta-galactosidase mRNA; Cre mRNA; mOrange mRNA; tdTomato mRNA; EYFP mRNA
Capping Cap 1
Modification Unmodified; N1-methyl-pseudouridine; 5-methoxyuridine
Module Type Peptide
Targeting Module KAA Peptide
Target Pancreatic cancer
Lipid Formulation DLin-MC3-DMA; LP-01; ALC-0315; SM102
Dye Unlabeled; DiR; DiD; DiO; DiI
Application Control; Targeted Delivery; Gene Therapy
Concentration 0.1 mg/mL; 0.2 mg/mL; Other (Please Specify)
Size 65-120 nm
PDI < 0.2
Zeta ± 20.0 mV
Encapsulate Efficiency >90%
Storage Store at 2-8°C
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