shRNA Adenovirus Serotype 5 (ΔE1/E3), p7SK-(Lypd1-shRNA-Seq1)(CAT#: AdV-SI3976WQ)
This product is a Lypd1-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The protein encoded by Lypd1 gene may play a role in the intracellular trafficking of alpha-4:beta-2 and alpha-7-containing nAChRs and may inhibit their expression at the cell surface. The expression of Lypd1-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
| Specifications | |
|---|---|
| Family | Adenoviridae |
| Species | Adenovirus |
| Serotype | AdV-5 |
| Backbone | AdV-5 (ΔE1/E3) |
| Tropism | Both nondividing and dividing cells |
| Modification | ΔE1/E3 |
| Insert | Lypd1-shRNA-Seq1 |
| Related Target/Protein | Lypd1 |
| Region | CDS |
| TargetSeq | CAGAAAGAAGTGATGGAGCAA |
| NCBI RefSeq | NM_145100 |
| Alternative Names | PHTS; LYPDC1 |
| Titer | >1*10^10 GC/mL |
