shRNA Adenovirus Serotype 5 (ΔE1/E3), p7SK-(Pof1b-shRNA-Seq1)(CAT#: AdV-SI3472WQ)

This product is a Pof1b-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The Pof1b gene is expressed at trace levels in mouse prenatal ovary and is barely detectable or absent from adult ovary, in human and in the mouse respectively. The expression of Pof1b-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Adenoviridae
Species Adenovirus
Serotype AdV-5
Backbone AdV-5 (ΔE1/E3)
Tropism Both nondividing and dividing cells
Modification ΔE1/E3
Insert Pof1b-shRNA-Seq1
Related Target/Protein Pof1b
Region CDS
TargetSeq GGATGAGATTGGCAATCATTA
NCBI RefSeq NM_181579
Alternative Names POF; POF2B
Titer >1*10^10 GC/mL
Related Diseases Premature ovarian failure
Target Gene
Gene ID 79983
Uniprot ID Q8WVV4

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