shRNA Adenovirus Serotype 5 (ΔE1/E3), pH1-(OR5M11-shRNA-Seq4)(CAT#: AdV-SI2420WQ)

This product is a OR5M11-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The OR5M11 gene encodes a olfactory receptor protein that interacts with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The expression of OR5M11-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Adenoviridae
Species Adenovirus
Serotype AdV-5
Backbone AdV-5 (ΔE1/E3)
Tropism Both nondividing and dividing cells
Modification ΔE1/E3
Insert OR5M11-shRNA-Seq4
Related Target/Protein OR5M11
Region CDS
TargetSeq GCCCTTCTACTCACTGAGTTT
NCBI RefSeq NM_001005245
Alternative Names OR11-199
Titer >1*10^10 GC/mL
Related Diseases Olfactory dysfunction
Target Gene
Gene ID 219487
Uniprot ID Q96RB7

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