shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(CCT3-shRNA-Seq1)(CAT#: AdV-SI2102WQ)
This product is a CCT3-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The protein encoded by CCT3 gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). The expression of CCT3-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
| Specifications | |
|---|---|
| Family | Adenoviridae |
| Species | Adenovirus |
| Serotype | AdV-5 |
| Backbone | AdV-5 (ΔE1/E3) |
| Tropism | Both nondividing and dividing cells |
| Modification | ΔE1/E3 |
| Insert | CCT3-shRNA-Seq1 |
| Related Target/Protein | CCT3 |
| Region | CDS |
| TargetSeq | GACATCGTTTCAGGCCACAAA |
| NCBI RefSeq | NM_005998 |
| Alternative Names | CCTG; PIG48; TRIC5; CCT-gamma; TCP-1-gamma |
| Titer | >1*10^10 GC/mL |
