shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(Gpatch2-shRNA-Seq4)(CAT#: AdV-SI1828WQ)

This product is a Gpatch2-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The Gpatch2 gene encodes a nuclear factor that may play a role in spermatogenesis and in tumor growth during breast cancer. Mutations in this gene cause Joubert syndrome (JBTS). The expression of Gpatch2-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.